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conferenceseries
.com
Volume 8
Journal of Biotechnology & Biomaterials
ISSN: 2155-952X
Pharma Biotech 2018
December 10-11, 2018
December 10-11, 2018 | Rome, Italy
23
rd
International Conference on
Pharmaceutical Biotechnology
A new nano technique tool in medical studies and diagnostic assays: A literature review
Vahabi Surena
Shahid Beheshti Medical University, Iran
A
tomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure
surface roughness. AFM is a kind of scanning probe microscope (SPM) and it’s a near field technique which is based
on the interaction between a sharp tip and the atoms of the sample surface. There are several methods and many ways to
modify its tip to investigate surface properties including friction and adhesion force measurements, viscoelastic properties and
determination of Young’s modulus and imaging magnetic or electrostatic properties. AFM can analyze any kind of samples
like polymers, adsorbed molecules, films or fibers, powders in air, controlled atmosphere or in liquid medium. In the past
decade, AFM has been emerged as a powerful tool to obtain nano structural details and biomechanical properties of biological
samples including biomolecules and cells. AFM application techniques and in particular its force measurement parts are not
still familiar to most of the clinicians. This paper reviews the literature regarding the main principles of AFM and highlights
the advantages of using AFM in biology, medicine and especially in dentistry. This literature review was performed through
e-resources including Science Direct, PubMed, Blackwell Synergy, Embase Elsevier and Google Scholar for the references
published in 1985 to 2010.
ivsure1@gmail.comJ Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C8-110