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Volume 6, Issue 4 (Suppl)
Clin Pharmacol Biopharm, an open access journal
ISSN: 2167-065X
Page 95
Euro Biopharma & Ethnopharmacology 2017
November 09-11, 2017
&
6
th
International Conference and Exhibition on
November 09-11, 2017 Vienna, Austria
4
th
EUROPEAN BIOPHARMA CONGRESS
PHARMACOLOGY AND ETHNOPHARMACOLOGY
Joint Event
Small is big: Magic microfluidic droplets
Liqiu “Rick” Wang
The University of Hong Kong, Hong Kong
D
roplets of nanoliter and subnanoliter are useful in a wide range of applications, particularly when their size is uniform
and controllable. Examples include biochemistry, biomedical engineering, food industry, pharmaceuticals, and material
sciences. One example of their many fundamental medical applications is the therapeutic delivery system for delivering site-
specific therapy to targeted organs in the body and as the carriers for newer therapeutic options. The size, the size distribution,
the generation rate and the effective manipulation of droplets at a scale of nano, pico, femto and even atto liters are critical in all
these applications. We make an overview of microfluidic droplet generation of either passive or active means and report a glass
capillary microfluidic system for synthesizing precisely controlled monodisperse multiple emulsions and their applications in
engineering materials, nanofluids, microfibers, embolic particles and colloidosome systems. Our review of passive approaches
focuses on the characteristics and mechanisms of breakup modes of droplet generation occurring in microfluidic cross-flow,
co-flow, flow-focusing, and step emulsification configurations. The review of active approaches covers the state-of-the-art
techniques employing either external forces from electrical, magnetic and centrifugal fields or methods of modifying intrinsic
properties of flows or fluids such as velocity, viscosity, interfacial tension, channel wettability, and fluid density, with a focus on
their implementations and actuation mechanisms. Also included is the contrast among different approaches of either passive
or active nature.
lqwang@hku.hkClin Pharmacol Biopharm 2017, 6:4(Suppl)
DOI: 10.4172/2167-065X-C1-026