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Volume 6, Issue 4 (Suppl)

Clin Pharmacol Biopharm, an open access journal

ISSN: 2167-065X

Page 95

Euro Biopharma & Ethnopharmacology 2017

November 09-11, 2017

&

6

th

International Conference and Exhibition on

November 09-11, 2017 Vienna, Austria

4

th

EUROPEAN BIOPHARMA CONGRESS

PHARMACOLOGY AND ETHNOPHARMACOLOGY

Joint Event

Small is big: Magic microfluidic droplets

Liqiu “Rick” Wang

The University of Hong Kong, Hong Kong

D

roplets of nanoliter and subnanoliter are useful in a wide range of applications, particularly when their size is uniform

and controllable. Examples include biochemistry, biomedical engineering, food industry, pharmaceuticals, and material

sciences. One example of their many fundamental medical applications is the therapeutic delivery system for delivering site-

specific therapy to targeted organs in the body and as the carriers for newer therapeutic options. The size, the size distribution,

the generation rate and the effective manipulation of droplets at a scale of nano, pico, femto and even atto liters are critical in all

these applications. We make an overview of microfluidic droplet generation of either passive or active means and report a glass

capillary microfluidic system for synthesizing precisely controlled monodisperse multiple emulsions and their applications in

engineering materials, nanofluids, microfibers, embolic particles and colloidosome systems. Our review of passive approaches

focuses on the characteristics and mechanisms of breakup modes of droplet generation occurring in microfluidic cross-flow,

co-flow, flow-focusing, and step emulsification configurations. The review of active approaches covers the state-of-the-art

techniques employing either external forces from electrical, magnetic and centrifugal fields or methods of modifying intrinsic

properties of flows or fluids such as velocity, viscosity, interfacial tension, channel wettability, and fluid density, with a focus on

their implementations and actuation mechanisms. Also included is the contrast among different approaches of either passive

or active nature.

lqwang@hku.hk

Clin Pharmacol Biopharm 2017, 6:4(Suppl)

DOI: 10.4172/2167-065X-C1-026