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Volume 6, Issue 4 (Suppl)
Clin Pharmacol Biopharm, an open access journal
ISSN: 2167-065X
Page 92
Euro Biopharma & Ethnopharmacology 2017
November 09-11, 2017
&
6
th
International Conference and Exhibition on
November 09-11, 2017 Vienna, Austria
4
th
EUROPEAN BIOPHARMA CONGRESS
PHARMACOLOGY AND ETHNOPHARMACOLOGY
Joint Event
Preparation and evaluation of silicon-containing coatings on bioabsorbable Mg/27.5HAnanocomposite
for bone tissue engineering
Shahrouz Zamani Khalajabadi
Malaysia-Japan International Institute of Technology, Malaysia
A
powder metallurgy technique to fabricate silicon and magnesium-oxide coated magnesium-based bionanocomposite with
hydroxyapatite has been developed. The sample coated with double layer MgO/Si was compared with bare Mg/27.5HA
nanocomposite and the sample coated by Si layer only. The surface microstructure and the cross section of bare and coated
samples before and after corrosion were examined by field-emission scanning electron microscopy (FE-SEM). The corrosion
performance of bare and coated samples was evaluated using potentiodynamic polarization, electrochemical impedance
spectroscopy and immersion tests. A decrease from 4.28 to 0.65 mm/year was observed in corrosion rate of Mg/27.5HA
nanocomposite with monolayer Si-coating. The results indicated that the corrosion resistance of Mg/27.5HA nanocomposite
was significantly improved byMgO/Si double layer coating. Moreover, MgO/Si coating is promising to enhance biocompatibility
of Mg/27.5HA nanocomposite for implant application. Antibacterial tests of the bare and coated samples revealed their
antibacterial activity against Staphylococcus aureus and Escherichia coli.
shahroozzamany@yahoo.comClin Pharmacol Biopharm 2017, 6:4(Suppl)
DOI: 10.4172/2167-065X-C1-026