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Volume 4 Toxicology: Open Access
ISSN: 2476-2067 Toxicology Congress 2018
March 12-14, 2018
March 12-14, 2018 Singapore
14th World Congress on
Toxicology and Pharmacology
A rare case of Modafinil dependence: A case report
Soma Sri Harsha, Krishnan V and Raman K
Saveetha Medical College and Hospital, India
Modafinil, a non-amphetamine psycho-stimulant, is indicated for narcolepsy, shift work sleep disorder and severe
obstructive sleep apnea syndrome. Modafinil is prescribed at the dose of 100 mg once in a day or as two doses, 12
hours apart in a day. Unlike classical stimulant medications like methylphenidate, Modafinil has been thought to produce
its wake-promoting effects independent of dopaminergic actions it has also been found that it reduces cocaine dependence
and withdrawal phenomenon. Modafinil is a very beneficial medication and this particular finding in and of itself should
not affect the way it is prescribed for the treatment of narcolepsy or even for the treatment in some instances off-label for
(attention-deficit/hyperactivity disorder) ADHD or for cognitive impairment in patients with schizophrenia, because under
those conditions, the patient is being monitored properly. However, it is directly pertinent to the concept of the misuse of
Modafinil, which is increasingly being utilized by healthy individuals with the expectation of improved cognitive performance.
Modafinil is claimed to have very low liability for abuse and dependence.
Biography
Soma Sri Harsha is currently pursuing his MBBS from Saveetha Medical College, SIMATS. His area of research is in the field of drug development, under the
mentorship of Dr. V Krishnan, Department of Pharmacology, SIMATS in India.
Soma Sri Harsha et al., Toxicol Open Access 2018, Volume 4
DOI: 10.4172/2476-2067-C1-005