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Volume 4 Toxicology: Open Access
ISSN: 2476-2067 Toxicology Congress 2018
March 12-14, 2018
March 12-14, 2018 Singapore
14th World Congress on
Toxicology and Pharmacology
Intravenous iron sucrose and oral iron therapy in iron deficiency anemia during pregnancy: A
comparative study in Indian population
Siva V K and Sankaran P K
Saveetha Medical College, India
Background: Nutritional anemia is one of major the contributory factor in high maternal mortality and morbidity in most of
the countries. Iron deficiency is the principle cause for nutritional anemia.
Objective: To compare the efficacy of oral iron therapy with intravenous iron therapy in the treatment of iron deficiency
anemia during pregnancy.
Methodology: This comparative study was undertaken at a tertiary care teaching hospital among 110 pregnant anemic patients
whose baseline hemoglobin and serum ferritin levels were recorded prior to treatment. The patients were divided into two
groups; group A (n=58) received intravenous iron-sucrose and group B (n=52) received oral iron therapy. The patients were
followed up for further investigations and side effects.
Results: Out of 110 patients, 50% had mild anemia (10.9-10 gm%), 34.5% patients had moderate anemia (7-9.9 gm%) and 15.5%
(6-6.9 gm%) patients had severe anemia. Group A showed statistically significant rise in hemoglobin regardless the severity.
Conclusion: Intravenous iron-sucrose administration increased hemoglobin level and serum ferritin levels more rapidly,
without any serious adverse effect in comparison with oral ferrous sulfate in women with iron deficiency anemia in pregnancy.
Biography
Siva V K is currently pursuing MBBS from Saveetha Medical College, SIMATS.
Siva V K et al., Toxicol Open Access 2018, Volume 4
DOI: 10.4172/2476-2067-C1-005