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Volume 4

Toxicology: Open Access

ISSN: 2476-2067

Toxicology Congress 2018

March 12-14, 2018

March 12-14, 2018 Singapore

14

th

World Congress on

Toxicology and Pharmacology

Analysis of chemicals present in the seeds of

Mucuna pruriens

by gas chromatographymass spectrometry

Joseph Swithin Fernando and Sankaran

Saveetha Medical College, India

M

ucuna pruriens

is a climbing legume used in the treatment of various ailments. It is commonly known as cowitch or

velvet bean. Traditionally, it was used in treating male infertility. The main aim of this study was to identify the bioactive

materials present in the methanol extract of

Mucuna pruriens

seeds by gas chromatography mass spectrometry (GC-MS)

technique. The analysis by GC-MS reveals the presence of 5 major compounds namely, pentadecanoic acid, 14-methyl-,

methyl ester, dodecanoic acid, 9,12-octadecadienoic acid (Z,Z)-, methyl ester, 9,12-octadecadienoic acid and 2-myristynoyl-

glycinamide. By comparing with the references of earlier studies, it was clear that these major compounds played a major role

in its neuro-protective, antioxidant, anti-inflammatory, anticancer, hepato-protective and antimicrobial effects. The presence of

antioxidants has been linked with neurogenesis in the brain. The presence of these compounds may authenticate the scientific

evidences of many of its proposed therapeutic potentiality of the seeds of

Mucuna pruriens

(MP).

Biography

Joseph Swithin Fernando is currently pursuing his MBBS from Saveetha Medical College. His area of research is applied pharmacology.

swithin.clarin@gmail.com

Joseph Swithin Fernando et al., Toxicol Open Access 2018, Volume 4

DOI: 10.4172/2476-2067-C1-005