Page 98
Volume 08
Clinical Pharmacology & Biopharmaceutics
ISSN: 2167-065X
Pharmacology 2019
World Heart Congress 2019
August 19-20, 2019
JOINT EVENT
conferenceseries
.com
August 19-20, 2019 Vienna, Austria
&
7
th
World Heart Congress
24
th
World Congress on
Pharmacology
Postoperative analgesic use pattern in a Tertiary Care Hospital in Bangladesh
Baqui QBOF*, Johora F, Ali M
and
Begum HA
University of Oxford, UK
Statement of the Problem
:. Postoperative pain is the most common problem following surgery whether patient
undergoes general anesthesia or subarachnoid block. Poorly controlled postoperative pain is as associated with
several complications like pneumonia, myocardial ischemia, paralytic ileus, thromoboembolism as well as an
increased chance of development of chronic pain. So effective postoperative analgesia is a crucial component of
surgical care. Different pharmacological modalities are available, and continue to evolve for reducing and managing
postoperative pain.
Purpose of this Study
: The objective of the present study was to find out the pattern of postoperative analgesic use in
first postoperative day in different surgeries in a tertiary care hospital of private setting in Bangladesh.
Methodology & Theoretical Orientation
: A prospective observational study was conducted among 600 patients
undergoing different surgeries in a tertiary care hospital of private setting in Dhaka, Bangladesh from November
2017 to April 2018. The demographic data, types of surgery, types of therapy, choice of analgesic were collected.
Findings
: Out of 600, 306 patients (51%) were male and 294 (49%) were female. Highest bulk of patients were from
department of general surgery (26%), followed by department of Urology (24.5%) and department of Obstetrics &
Gynecology (22.5%). Majority of patients were age group 30-39 years (26%), followed by 50-59 years (23.5%) and
40-49 years (21.5%). 248 patients (41.33%) had received monotherapy of analgesic drug, whether 276 patients (46%),
57 patients (9.5%) and 19 patients (3.2%) received two drugs combination, three drugs combination, four drugs
combination respectively. Opioid analgesic, Pethidine, was the most commonly utilized analgesic as monotherapy
(69.3%), followed by dexmedetomidine (20.2%) and epidural analgesic, Bupivacaine (19.4%). Combination of
pethidine and paracetamol (48.2%) was the most common followed by combination of pethidine and ketorolac
(12.7%) as two drug combination. As three drug combination, pethidine, paracetamol and diclofenac (35.1%) was
widely used.
Conclusion & Significance
: Pethidine was the preferred analgesic for first postoperatve day in different surgical
cases.
Clin Pharmacol Biopharm, Volume 08