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Volume 08
Clinical Pharmacology & Biopharmaceutics
ISSN: 2167-065X
Pharmacology 2019
World Heart Congress 2019
August 19-20, 2019
JOINT EVENT
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August 19-20, 2019 Vienna, Austria
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7
th
World Heart Congress
24
th
World Congress on
Pharmacology
Menopausal status is not associated with hypertension in post-menopausal women
Namrata Kafle
Padma Nursing College, India
Introduction
: Menopause is a inevitable physiological phenomenon inwhich cardiovascular risk factor (CRF) factors
association is reported, but age at menopause (AAM) varies considerably and could affect the risk among post-
menopausal women. The aim of the study was to clarify whether AAM is associated with hypertension, independent
of chronological age, lifestyle and hormone replacement therapy (HRT), in Nepalese women.
Methods
: A cross-sectional study was conducted using the baseline survey in 60 female among them 30 were post
menopausal aged (45-55) study group and 30 pre menopausal aged (35-44) women considered to be control group.
The prevalence of hypertension in AAM groups were compared by using statistical analysis. Daily lifestyle such as
smoking, alcohol consumption, and doing brisk physical activity and women under oral Contraceptive pill were not
included in this study.
Results
: The estimated risk (odds ratio: OR) was significantly higher in post-menopausal women and linearly
elevated according to the AAM groups, and the late AAM group was more likely to have hypertension however, after
adjustment for age, BMI (kg/m(2)), HRT and lifestyle, AAM showed no significant association with cardiovascular
variables such as systolic, diastolic and pulse pressure when just considered the menopausal status, therefore AAM
group is not associated with increased risk of hypertension compared with premenopausal control group attributed
just because of menopausal status.
Conclusions
: There is no any association of hypertension relevant to menopausal status confounding other
parameters such as age, BMI, life style and HRT therapy in the post-menopausal women.
Clin Pharmacol Biopharm, Volume 08