pharmacology-world-heart-congress-2019-posters-abstracts

Page 82

Volume 08

Clinical Pharmacology & Biopharmaceutics

ISSN: 2167-065X

Pharmacology 2019

World Heart Congress 2019

August 19-20, 2019

JOINT EVENT

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August 19-20, 2019 Vienna, Austria

World Heart Congress

World Congress on

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Evaluation of the effect of HFRT on the anthropometric obesity parameters in patients of chronic heart

failure-a retrospective analysis

Gurudatta Amin, Rohit Sane

and

Rahul Mandole

Madhavbaug Cardiac Care Clinics and Hospital, India

Statement of the Problem

: Chronic heart failure (CHF) is a common cause of mortality and morbidity. Obesity

influences the CHF development and prognosis. This study was conducted to assess effect of Heart failure reversal

therapy (HFRT), a combination of panchakarma and allied therapies, on anthropometric parameters in CHF patients.

Methodology & Theoretical Orientation

: This retrospective study was conducted on data of patients who visited

Madhavbaug clinics in Maharashtra, India between July-December 2018. Selection was based upon the availability

of complete baseline (day 1 of HFRT) and follow-up data (day 30 of HFRT) of CHF patients who were admitted for

minimum five days for HFRT.

Findings

: Out of 147 patients, 74.15%were males with mean age 59.15+10.28 years. There was statistically significant

decrease (p<0.05) in both mean BMI and abdominal girth at day 30 of HFRT. 42 of 147 patients (28.57%) had

hypertension (HTN) with CHF, 22 patients (14.97%) had diabetes mellitus (DM) and 61 patients (41.49%) had both

HTN and DM. In all these sub-groups, mean BMI and abdominal girth was significantly decreased (p<0.05) at day

30. Strong positive correlation was found between BMI and abdominal girth on day 1 (R=0.9, P<0.05) and day 30

(R=0.83, P<0.05) by Pearson’s correlation. Similar correlation was found between the two parameters in subsets of

CHF patients having HTN or DM or both DM and HTN (p<0.05).

Conclusion & Significance

: HFRT decreased BMI and abdominal circumference significantly in CHF patients,

irrespective of the presence of HTN or DM. Both the anthropometric parameters correlated strongly in all co-

morbidity subsets of CHF patients.

Clin Pharmacol Biopharm, Volume 08