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Volume 8
Journal of Clinical & Experimental Pharmacology
Pharmacology and Medicinal Chemistry 2018
October 18-19, 2018
October 18-19, 2018 Dubai, UAE
International Conference on
18
th
International Conference on
&
Joint Meeting on
Pharmacology and Toxicology
Medicinal and Pharmaceutical Chemistry
Physicochemical and pharmaceutical properties of gelatin extracted from goat skin: The new excipient
in pharmaceutical and food dosage form
Zilhadia Anwar Hasibuan
1
, Yahdiana H
2
, Irwandi J
3
and Effionora A
2
1
Syarif Hidayatullah State Islamic University, Indonesia
2
University of Indonesia, Indonesia
3
International Islamic University Malaysia, Malaysia
G
enerally the gelatin used in pharmaceutical and food dosage form was obtained from bovine and porcine. This research
explored the new alternative source of gelatin, namely goat skin. Goat skin was soaked in hydrochlorid acid and then
gelatin was extracted using warm water. Their physicochemical and pharmaceutical properties were investigated. A yield of
12.74±0.87 g/100 g skin sample on the basis of wet weight was obtained. Organoleptic of goat gelatin powder is a vitreous, brittle
solid faintly yellow in color, nearly tasteless and odorless. The result of physicochemical properties exhibited the following:
sulfide content of 7.18±0.68 ppm, lead, zinc and copper were not detected. % transmittance of goat gelatin solution revealed
clarity value was 56.9±0.95. pH, moisture and ash content were 5.11±0.9, 9.23±0.9 and 0.18±0.16, respectively. The results of
pharmaceutical properties including emulsion activity index, foaming properties, gel strength and viscosity were 77.23±23,
118.87±0.12, 307.67±2.64 and 25.5±1.83, respectively. The microbial assay showed microbes were not detected. All of these
physicochemical and pharmaceutical properties of goat skin gelatin indicated that it meets the defined requirements of a good
gelatin and could use as alternative material in pharmaceutical and food dosage form.
Biography
Zilhadia Anwar Hasibuan has completed his PhD from Faculty of Pharmacy University of Indonesia. She is a Lecturer and the Director of Pharmacy Medicine
Laboratory Syarif Hidayatullah State Islamic University. She has published several papers in reputed journals and as presenter in several international conferences.
zilhadia@uinjkt.ac.idZilhadia Anwar Hasibuan et al., Clin Exp Pharmacol 2018, Volume 8
DOI: 10.4172/2161-1459-C3-034