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Euro Biotechnology 2016
November 07-09, 2016
Volume 6, Issue 7(Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
conferenceseries .com
November 07-09, 2016 Alicante, Spain
12th Euro Biotechnology Congress
Magdalena Zuk et al., J Biotechnol Biomater 2016, 6:7(Suppl)
Chalcone synthase regulates flax metabolism and positively diversify linseed products
Magdalena Zuk and Jan Szopa
Wroclaw University, Poland
The chalcone synthase (CHS) gene controls the first step in the flavonoid biosynthesis route, the metabolic pathway in
which anthocyanins, phenolic acids, lignins, simply phenols were produced. The transgenic plants with overexpression
of the heterological CHS gene were generated, leading to the increased synthesis of flavonoids, high antioxidant potential
and improve the properties of products obtained such as flax fiber and oil. At the same time, repressing the endogenous CHS
gene should verify the results of research on its overexpression and provide information on its potential role of CHS in the
redistribution of substrates and diversification of metabolites within the phenylpropanoid pathway, especially in relation to
lignins. In flax, CHS down-regulation resulted in tannin accumulation and reduction in lignin synthesis but plant growth was
not affected. This suggests that lignin content and thus cell wall characteristics might be modulated through chalcone synthase
gene activity. The important role of CHS gene is in regulation of cell wall sensing as well as polymer content and arrangement.
CHS-reduced flax also showed significant changes in morphology and arrangement of the cell wall. The additional result of
this work was indication of relationship between the expression of the CHS gene and the metabolism and stability of fatty acid
in flax. Plant with reduction of CHS produced oil with ideal proportion of ω6/ω3 fatty acids. Summing up CHS modification
induces signal transduction cascade that leads to modification of flax metabolism in a wide range and positively diversify its
products.
Biography
Magdalena Zuk has completed her PhD from Wroclaw University in 2003 and worked on diversification of secondary metabolites in crop plants (flax, potato). She
has published more than 35 papers in reputed journals and is a Member of Board of Linum Foundation, a non-profit organization promoting pro-health use of flax
products.