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conferenceseries
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Volume 7, Issue 5 (Suppl)
J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
Biotechnology 2017
November 13-14, 2017
November 13-14, 2017 Osaka, Japan
19
th
World Congress on
Biotechnology
Si- and Fe-substituted beta-tricalcium phosphate: Synthesis, characterization and
in vitro
properties
Kyung-Hyeon Yoo, Hyeonjin Kim, Youngjun Kim and Seog-Young Yoon
Pusan National University, South Korea
T
he aim of this study was to investigate the effects of Si and Fe ions in β-TCP on the physical and chemical properties. Beta-
tricalcium phosphate (β-TCP) has been known as biodegradable material for temporary medical devices. Enhancing the
strength and osteoconduction properties of β-TCP is important for their applications. To modify mechanical properties and
in vitro
behavior, Si and Fe ions were substituted in β-TCP. The Si- and Fe- substituted β-TCP powder were synthesized by
co-precipitation method. Crystal structure and thermal properties of Si- and Fe-substituted β-TCP were investigated by using
X-ray diffraction combined with Rietveld refinement analysis and differential thermal analysis (DSC) to compare the effects
of substituted elements on β-TCP. Moreover, MTT assay, alkaline phosphate (ALP) staining confirmed the cytotoxicity, cell
differentiation and cell proliferation.
Biography
Kyung-Hyeon Yoo has completed her BS from Pusan National University.
seweet07@pusan.ac.krKyung-Hyeon Yoo et al., J Biotechnol Biomater 2017, 7:5 (Suppl)
DOI: 10.4172/2155-952X-C1-083