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Volume 7, Issue 5 (Suppl)

J Biotechnol Biomater

ISSN: 2155-952X JBTBM, an open access journal

Biotechnology 2017

November 13-14, 2017

November 13-14, 2017 Osaka, Japan

19

th

World Congress on

Biotechnology

Preparation of high elastic polyurethanes based on polycaprolactone diol, 1,6-hexamethylene

diisocyanate, isosorbide derivative and their biocompatible properties

Suk-Min Hong

1

, Jae-Ryung Cha

1

, Jun-seop Im

2

, Gwang-seok Song

2

and Myoung-Seon Gong

1

1

Dankook University, South Korea

2

Samyang Corporation, South Korea

I

n this study, various chain lengths of 1' isosorbide (IC 22, IC 32, IC 52, IC 102, IC 29, IC 39, IC 59, IC 89) was prepared from

isosorbide and ethylene oxide or propylene oxide in the presence of K

2

CO

3

. The successful synthesis of 1' isosorbide (IC

22, IC 32, IC 52, IC 102, IC 29, IC 39, IC 59, IC 89) was confirmed by

1

H-nuclear magnetic resonance (

1

H-NMR). Bio-based

high elastic polyurethanes were made using polycaprolactone diol, various chain lengths of 1' isosorbide and hexamethylene

diisocyanate. The polyurethanes were produced by one-shot bulk polymerization without catalyst. The successful synthesis

of the polyurethanes was confirmed by FT-IR and GPC. The thermal and mechanical properties were characterized by

thermogravimetric analyzer (TGA), differential scanning calorimetry (DSC). The mechanical properties were measured using

universal testing machine (UTM). Degradation test was performed using PBS solution and biocompatibilities of PUs were

tested using C2C12 for biomedical applications.

Biography

Suk Min Hong is a Doctoral student in the Department of Nanobiomedical at Dankook University. His research interests are in polyurethanes, bio-polyurethanes,

isosobides and natural polymers.

wwwwwppp@hanmail.net

Suk-Min Hong et al., J Biotechnol Biomater 2017, 7:5 (Suppl)

DOI: 10.4172/2155-952X-C1-083