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Volume 7, Issue 5 (Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal Biotechnology 2017
November 13-14, 2017
November 13-14, 2017 Osaka, Japan
19th World Congress on
Biotechnology
Preparation of biocompatible shape-memory polymers using polycaprolactone and isosorbide based
polyurethane blends for biomedical application
Yoon-Suk Joo, Hyeon-A Kim, Nam-Yoon Kim, Jae-Ryung Cha and Myoung-Seon Gong
Dankook University, South Korea
In this study, biocompatible and biodegradable polyurethane (PU) and polycaprolactone (PCL) were blended to enhance
shape memory and mechanical properties. PCL (M.W: 80,000) was used as a hard segment and PU synthesized from
isosorbide, which is non-toxic and enzyme decomposition, was used as a soft segment. The obtained PU/PCL blends with
weight ratios of (3/7), (5/5) and (7/3) were investigated for their thermal properties, mechanical properties and shape memory
behavior. Thermal properties of blends were investigated using differential scanning calorimetry (DSC), thermal gracimetric
analysis (TGA) and shape memory properties were measured using dynamic mechanical analysis (DMA). The biodegradation
test performed at 37 °C in phosphate buffered solution showed a mass loss of 2-4% for the obtained PU/PCL blends after 6
weeks. Finally, MC3T3-E1 cells cultured on PU/PCL blends showed high biocompatibility.
Biography
Yoon-Suk Joo is currently pursuing Master's degree at Dankook University. His research interest is in polymers used as biomaterials and has biocompatible
polyurethane synthesis.
Yoon-Suk Joo et al., J Biotechnol Biomater 2017, 7:5 (Suppl)
DOI: 10.4172/2155-952X-C1-083