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Journal of Biotechnology & Biomaterials | ISSN: 2155-952X | Volume: 8
3rd World Biotechnology Congress
December 03-04, 2018 Sao Paulo, Brazil
The effect of growth conditions on the active compounds found in medicinal plants
Alexandra C H F Sawaya
University of Campinas, Brazil
Statement of the Problem: In spite of the world-renowned Brazilian biodiversity and the therapeutic potential of its medicinal
plants, lack of information regarding the correct identification and quality control of these species is an obstacle to their use. The
use of medicinal plants in Brazilian health policy has been increasingly promoted by governmental guidelines and syrup using
two species of Guaco is currently supplied by the Health System (SUS) as a cough medicine. Although the commercialization of
herbal medicines in Brazil is governed by several laws, the quality of rawmaterial interferes with the safety, quality and expected
efficacy of herbal medicines. Different conditions of cultivation of medicinal plants result in variations in the concentrations of
active principles and may affect these parameters.
Methodology and Theoretical Orientation: The variation of secondary metabolites of these two species was influenced by
the variations in the cultivation conditions of: temperature, luminosity, soil, mechanical damages and water supply, as well as
field monitoring of fluctuations due to the period of collection or seasonality. Extracts were made from the leaves and their
composition was evaluated by liquid chromatography with mass spectrometry, following the content of its marker (coumarin)
as well as the profile of the other components.
Conclusion and Significance: The highest variation among the secondary metabolites was found between the two guaco
species, M. glomerata and M.laevigata, so they cannot be used interchangeably. In seasonality, M. laevigata seems to suffer
mainly from air temperature in the production of secondary metabolites; already for M. glomerata it was possible to notice the
influences of the flowering in the decrease of chlorogenic acid. No significant variations were observed in relation to collection
time (morning, noon or afternoon). Regarding the treatments, a single condition was not found to increase all the metabolites
of therapeutic interest of these species.
Biography
Alexandra C H F Sawaya holds a Bachelor's degree in Pharmacy and Biochemistry from the faculty of Pharmaceutical Sciences of the University of Sao Paulo, a
Master's degree in Pharmaceutical Sciences from Sao Francisco University, a PhD in Chemistry from the State University of Campinas and postdoctoral studies
in the Department of Plant Biology (UNICAMP) between 2008-2013. She worked as a Lecturer at UNIBAN in the Pharmacy and Biomedicine Courses (2006-8)
and in the Professional Master's Degree in Pharmacy. She is currently Assistant Professor at the Pharmacy Course at UNICAMP and active in the programs of
Biosciences and Technology of Bioactive Products and Plant Biology of IB, UNICAMP. Her area of expertise is of mass spectrometry and chromatography in studies
of bee products, food, herbs and herbal products.
Alexandra C H F Sawaya, J Biotechnol Biomater 2018, Volume: 8
DOI: 10.4172/2155-952X-C7-106