world-biomarkers-pharma-biotech-2017-posters

Volume10, Issue 12 (Suppl)

J Proteomics Bioinform, an open access journal

ISSN: 0974-276X

Page 104

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World Biomarkers & Pharma Biotech 2017

December 07-09, 2017

December 07-09, 2017 | Madrid, Spain

International Conference on

PHARMACEUTICAL BIOTECHNOLOGY

WORLD BIOMARKERS CONGRESS

JOINT EVENT ON

J Proteomics Bioinform 2017, 10:12(Suppl)

DOI: 10.4172/0974-276X-C1-110

A comparison between biopharmaceuticals and pharmaceuticals in cancer treatment

Elham Pahlevani

University of Medical Sciences, Iran

ndoubtedly, cancer is one of the main causes of morbidity and mortality around the world. Common treatments of cancer

such as surgery, radiotherapy and chemotherapy are effective in curing cancer at early disease stages; however, they cannot

completely eradicate it in metastatic condition. For example, the success of chemotherapy has been diminished due to loss of its

selectivity and specificity, thereby the administration of dose to patients should be limited because of the toxicity to normal cells.

Thus, utilizing targeted anticancer biopharmaceuticals (monoclonal antibodies, non-antibody proteins and small molecules) can

be effective in controlling the progression of cancer, having less side effects and survival of cancerous patients. Biopharmaceuticals

are macro molecules-based therapeutic drugs which are manufactured in or extracted from biological sources. They are 200-1000

times larger than traditional small molecule drugs. Furthermore, they do not arise from simple chemical processes like traditional

pharmaceuticals. So, it makes much greater complexity in their structure than the latter. On the other hand, pharmaceuticals, known

as medicine or drug, are a principal component of traditional medicine and include a broad spectrum of medicines. They come

from chemicals. In fact, they make up over 90% of the drugs on the market. Biopharmaceuticals and pharmaceuticals differ not only

in terms of size, but also in the methods of processing, behavior and type of action in the body and so on. In this paper, features

of biopharmaceuticals and pharmaceuticals for the treatment of cancer are explained and compared. These items include safety

and efficacy (immunogenic response), bioactivity, side effects, cost, dosage rate and access rate. Having knowledge about effective

pharmaceutical methods for the treatment of cancer can be very helpful in choosing an efficient method and its results can be more

productive and accurate than conventional methods of cancer treatment.