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Notes:
Volume 7, Issue 3 (Suppl)
J Nutr Disorders Ther, an open access journal
ISSN: 2161-0509
Page 83
JOINT EVENT
&
July 27-29, 2017 Rome, Italy
Advances in Natural Medicines Nutraceuticals & Neurocognition
14
th
International Conference on Clinical Nutrition
13
th
International Congress on
Lowerenergy intakepredicts 10-yearmortality inpatientswithend-stage renal diseaseonhemodialysis
Yongsoon Park
1
, Shin Sook Kang
2
and
Jai Wone Chang
2,3
1
Hanyang University, Korea
2
Asan Medical Center, Korea
3
University of Ulsan, Korea
P
rotein-energy wasting (PEW) is associated with mortality in patients with end-stage renal disease (ESRD) on maintenance
hemodialysis. The correct diagnosis of PEW is extremely important in order to predict clinical outcomes. However, it is
unclear which parameters should be used to diagnose PEW. Therefore, this retrospective observational study investigated the
relationship between mortality and nutritional parameters in ESRD patients on maintenance hemodialysis. A total of 144
patients were enrolled. Nutritional parameters, including body mass index, serum albumin, dietary intake, normalized protein
catabolic rate (nPCR), and malnutrition inflammation score (MIS), were measured at baseline. 53 patients died during the
study. Survivors had significantly higher nPCR (1.10±0.24 g/kg/day vs. 1.01±0.21 g/kg/day; p=0.048), energy intake (26.7±5.8
kcal/kg vs. 24.3±4.2 kcal/kg; p=0.009) and protein intake (0.91±0.21 g/kg vs. 0.82±0.24 g/kg; p=0.020), and lower MIS (5.2±2.3
vs. 6.1±2.1, p=0.039). In multivariable analysis, energy intake < 25 kcal/kg (HR 1.860, 95% CI 1.018–3.399; p=0.044) and MIS
> 5 (HR 2.146, 95% CI 1.173–3.928; p=0.013) were independent variables associated with all-cause mortality. These results
suggest that higher MIS and lower energy intake are harmful to ESRD patients on maintenance hemodialysis. Optimal energy
intake could reduce mortality in these patients.
Biography
Yongsoon Park had completed her PhD from Washington State University and Postdoctoral studies from Mayo Clinic. She is a Professor at Hanyang University,
Seoul, Korea. She has published more than 110 papers in reputed journals and has been serving as an Editorial Board Member of
Journal of Medicinal Food,
Journal of nutrition and Practice, Korean Journal of Medicinal Crop Science, and Korean Journal of Obesity.
yongsoon@hanyang.ac.krYongsoon Park et al., J Nutr Disorders Ther 2017, 7:3(Suppl)
DOI: 10.4172/2161-0509-C1-007