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Volume 5, Issue 3 (Suppl)
Mod Chem Appl, an open access journal
ISSN: 2329-6798
Global Chemistry 2017
September 04-06, 2017
September 04-06, 2017 | London, UK
5
th
Global Chemistry Congress
Anovel continuous flowroute for the synthesis of phase pure brushite calciumphosphate nanoparticles
Aneela Anwar
University of Engineering and Technology, Pakistan
D
icalcium phosphate dehydrate: CaHPO4.2H2O (brushite) nanoparticles (~ 35 nm) were rapidly synthesised using a rapid
novel two pump continuous plastic flow synthesis (CPFS) at room temperature (22 °C) in 3 minutes residence time at
the conditions of pH 5.5 from aqueous solution of calcium nitrate tetrahydrate and diammonium hydrogen phosphate. The
product was collected as a phase pure material with Ca:P molar ratio of 0.8 , without the need for an ageing step. Highly
crystalline brushite nanoparticles exhibiting spherical chain like morphology were observed, which had high surface area of
160 m2 g-1. These brushite nanoparticles were also transformed to monetite and calcium pyrophosphates by additional steps
such as heat treatments. The final product was physically characterized by using different techniques such as transmission
electron microscopy (TEM), BET surface area analysis, X-ray diffraction analysis (XRD), and FTIR spectroscopy. In addition,
X-ray photoelectron spectroscopy (XPS) was also used to analyze the chemical structure. The employed system shows promise
for the rapid production of high surface area, smaller nanoparticles for use in bone regeneration strategies.
a.anwar@uet.edu.pkMod Chem Appl 2017, 5:3(Suppl)
DOI: 10.4172/2329-6798-C1-006