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CNS 2016
December 05-07, 2016
Volume 7, Issue 5(Suppl) J Neurol Neurophysiol
ISSN: 2155-9562 JNN, an open access journal
conferenceseries .com
December 05-07, 2016 Dubai, UAE
2nd International Conference on
Central Nervous System Disorders & Therapeutics
Ahad Abdullah et al., J Neurol Neurophysiol 2016, 7:5(Suppl)
Intracranial teratoma: Case series and review of literature
Ahad Abdullah1, Hussein Algahtani 2, Abdulrahman Bazaid1, Bader Shirah2 and Bashair Ibrahim3
1Batterjee Medical College, KSA
2King Saud bin Abdulaziz University for Health Sciences, KSA
3King Abdulaziz University, KSA
Background: Teratoma is a common form of germ cell tumors composed of multiple tissues foreign to the site in which
arise with histological representation of all three germ cell layers (ectoderm, mesoderm, and endoderm). It was derived from
the Greek word teraton meaning a “monster”. It commonly presents during infancy and childhood and accounts for 2% of
intracranial tumors in patients under the age of 15 years. Intracranial teratomas are very rare.
Methodology: This is a retrospective study done in king AbdulazizMedical city- Jeddah, and it was approved by the Institutional
review board (IRB) of King Abdullah international Medial Research Centre (KAIMRC). All 69 cases with the diagnosis of
teratoma during the period of January 2005 to June 2016 were reviewed. Clinical, demographic, radiological and treatment
details of the patines were retrieved from the medical records (both hard and electronic). A sub-group analysis was also made
for all 3 cases diagnosed as intracranial teratoma.
Results: A total number of 69 patients were reviewed, 11 (15.9%) male and 58 (84.1 %) female. The age range is 1 day to 76
years. The sites of pathology of these teratomas were as follows: ovarian: 50 (72.5%), central nervous system (CNS) 3 (4.3%),
kidney 1(1.4%), lumbosacral 1(1.4%), neck 2 (2.9 %), retro-peritoneum 3 (4.3%), testis 2 (2.9%) sacrococcygeal 4 (5.8%) and
mediastinal 3 (4.3%). The three patines with CNS teratomas had different sites as-well, 1 cerebral hemisphere, 1 posterior fossa
and 1 pineal gland. There was 1 (33.3 %) mature and 2 immature (66.6 %) , 1 (33.3%) cystic and 2 (50%) solid.
Conclusion: Intracranial teratomas 4% of all types of teratomas. The prognosis is dependents on location, size and surgical
experience, short coming of this study are small number of patients, lack of statistics regarding other forms of brain tumors
and being a single study.
Biography
Ahad Abdullah is a medical intern currently training at King Abdulaziz Medical City National Guard in Jeddah, Saudi Arabia. She obtained her MBBS degree in year
2016 from Battarjee Medical College in Jeddah, Saudi Arabia. She attended several seminars, courses and workshops related to research methodology. She is
determined to pursue her career as a physician, surgeon and researcher.