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Volume 7, Issue 6 (Suppl)

J Biotechnol Biomater, an open access journal

ISSN: 2155-952X

World Biotechnology 2017

December 04-05, 2017

2

nd

World Biotechnology Congress

December 04-05, 2017 | Sao Paulo, Brazil

Commercial polyester fabric repair of abdominal defects and hernias

M Shokry

Cairo University, Egypt

H

ernias are common surgical affections of human and animals and their treatments may vary from simple herniorrhaphy to

hernioplasty with prosthetic materials. This work was designed to study the feasibility of using commercial polyester fabric

(CPF) as a prosthetic mesh for reconstruction of abdominal hernias and defects in experimental and clinically affected animals. The

subjects of the experimental work were 12 dogs, 3 goats and 3 donkeys. Following anesthesia, an artificial abdominal defect, measured

5X12 cm in dogs and goats and 12X20 cm in the donkeys, was produced by resection of a piece of abdominal muscle in 3 different

abdominal regions, such as the epigastrium (3 cases), the mesogastrium (12 cases) and the hypogastrium (3 cases). An appropriate

piece of sterilized CPF was implanted either in 2 layers in small animals or in 4 layers (folded) in large animals in the abdominal

defects. The techniques of implantation used, were reteroperitoneal (6 cases) in which the CPF was implanted between the internal

rectus sheath and peritoneum, intra-peritoneal implantation either with (3 cases) or without (3 cases) mentalization; and double

sandwish (3 cases) using 2 layers. Morphological and histo-pathological examinations were carried out on full thickness sections after

euthanasia at 1, 2 ,3 ,4, 5 and 6 months postoperatively. The clinically affected cases comprised different species of animals at different

locations. Gross examination of the abdominal wall at the experimental implantation site at monthly intervals for 6 months showed

the unaltered integrity of the CPF and uniform infiltration of the prosthetic material with a layer of white connective tissue of variable

thickness (4 to 10 cm). Histological features correlated well with the gross examination. Complications related to herniorrhaphy in

the clinical cases have been rarely serious. In conclusion, CPF has excellent biocompatibility and no adverse histological changes. Low

cost CPF therefore offers a worthwhile alternative prosthesis for mesh herniorrhaphy

Biography

M Shokry is currently a Professor Emeritus, Dept. of Vet Surgery, Faculty of Veterinary Medicine at Cairo University in Egypt. He has published more than 100 Articles in

the various national and International journals.

mshokry@cu.edu.eg

M Shokry, J Biotechnol Biomater 2017, 7:6 (Suppl)

DOI: 10.4172/2155-952X-C1-086