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Volume 7, Issue 6 (Suppl)
J Biotechnol Biomater, an open access journal
ISSN: 2155-952X
World Biotechnology 2017
December 04-05, 2017
2
nd
World Biotechnology Congress
December 04-05, 2017 | Sao Paulo, Brazil
Antheraea mylitta
cocoonase: A boon in silk industry
Dev Mani Pandey
1
, Sneha Prasad
1
, Priya Porwal
1
, Ajit Kumar Sinha
2
and
Jay Prakash Pandey
2
1
Birla Institute of Technology, India
2
Central Tasar Research and Training Institute, India
S
ericulture, both an art and a science of raising silkworms for silk production, has better prospects in developing countries as silk
production is highly economical. Silkworm species vary in terms of the quality of silk they produce and the food plants they
consume. Wild silkmoths include tasar silkworm, eri-silkworm, oak-tasar silkworm and muga silkworm. The Indian tasar silkworm.
Antheraea mylitta
is a natural fauna of tropical India, represented by 44 ecoraces. Wide distribution and polyphagy of this insect
species has resulted in extensive variation in the population. Tasar cocoons are reported to be largest among all the silk-producing
insects in the world. Cocoon, shelter for larva development to silk moth, contains fibrous protein, fibroin and is coated by the globular
protein, sericin. The escape of the silk moth from cocoon requires the action of cocoonase enzyme secreted by the pupa. Cocoonase is
a protease enzyme which hydrolyses sericin, soften cocoon and later they escape out. Seeking this vital function, the study focuses on
the production of active recombinant
Antheraea mylitta
cocoonase and its post translationmodification (PTM). PTM can significantly
modulate the integral properties of protein affecting its stability, interaction and providing proper folding. Several PTMs such as
phosphorylation, SUMOylation, myristoylation and glycosylation are being checked. Obtained detailed findings will be discussed
Biography
Dev Mani Pandey is interested in the research areas and scientific expertise includes: molecular biology, functional genomics, stress physiology and bioinformatics
approaches on plants like rice, groundnut, medicinal plants etc., using recent biotechnological tools. He is also associated with Central Tasar Research and Training
Institute, Ranchi, India for sericulture related research. He is also actively involved in research, teaching and other department and institute activities.
dmpandey@bitmesra.ac.inDev Mani Pandey et al., J Biotechnol Biomater 2017, 7:6 (Suppl)
DOI: 10.4172/2155-952X-C1-086