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Veterinary Summit 2016

November 14-16, 2016

Volume 7 Issue 7(Suppl)

J Vet Sci Technol

ISSN: 2157-7579 JVST, an open access journal

conferenceseries

.com

November 14-16, 2016 Atlanta, USA

6

th

Global Veterinary Summit

J Vet Sci Technol 2016, 7:7(Suppl)

http://dx.doi.org/10.4172/2157-7579.C1.022

Comparison of metabolic profile in Brown Swiss cows that bearing male and female calf in

periparturient period

Emrah Hicazi Aksu, Ali Dogan Omur, Fatih Mehmet Kandemir and Akin Kirbas

Ataturk University, Turkey

T

his study aimed to investigate trace element levels, metabolic and hormone profiles of male calf bearing (MCB) and female

calf bearing (FCB) cows in periparturient period. In the present study, 20 Brown Swiss (4-5 years old and 500-550 kg

weighing) cow was used as animal material. Blood samples were collected on prepartum 21th day. According to birth records

samples were classified as MCB (n=11) and FCB (n=9). 9 of the cows were selected as the control group (C) and after 21 days

from the births blood samples were collected. Biochemical analyses (glucose, urea, cholesterol, creatine, Ca, Cl, Na, P, K, Fe,

Mg, FSH, LH and progesterone) of the samples were done. Our findings showed that glucose, Na, Cl, and progesterone levels in

both pregnancy groups were significantly higher than the control group. Alternatively, cholesterol levels of the both pregnancy

groups were significantly lower when compared to the C group. Urea level in MCB group was significantly higher than in both

FCB and C group. Ca levels in MCB group were similar with FCB group but higher than the C group. On the other hand, there

were no any differences among the all groups for creatine, K, P, Mg, Fe, FSH and LH levels.

emrahaxu@hotmail.com

Investigation of the effects of chrysin on paracetamol-induced liver damage in rats

Fatih Mehmet Kandemir, Eyup Eldutar and Sefa Kucukler

Ataturk University, Turkey

I

n this study, it was aimed to investigate the effects of chrysin (CH) on the liver toxicity of high doses of paracetamol (PCM).

A total of 35 Sprague Dawley rats were used in this study, including 5 groups with 7 rats in each group. The control group

(healthy) was given orally saline (SF) only for 6 days but not any other drugs. The CH group was given 50 mg/kg/day of CH

orally for 6 days. The PCM group was given SF orally for 6 days and then 500 mg/kg single oral dose of PCM 30 min after SF

treatment on the 6

th

day. The PCM+CH 25 mg/kg/day group was given CH (25 mg/kg/day) orally for 6 days and then single

oral dose of PCM (500 mg/kg/day) 30 min after CH treatment on the 6

th

day by gavage. Similarly, the PCM+CH 50 mg/kg/

day group was given CH (50 mg/kg/day) orally for 6 days and then single oral dose of PCM (500 mg/kg/day) 30 min after CH

treatment on the 6

th

day by gavage. It was determined that in the PCM group compared with the control group, the serum ALP,

ALT and AST activities increased and that the liver SOD, CAT, GPx activities and GSH levels were decreased and the liver

MDA levels were increased (P<0.05 ). It was found that in PCM+CH-25 and CH-50 groups compared to the PCM group, the

serum ALP, ALT, AST activities were decreased and the liver SOD, CAT, GPx activities and GSH levels were increased and the

liver MDA levels were decreased (P<0.05). It was concluded that both doses of CH treatments were effective on PCM-induced

liver toxicity.

fmehmet.kandemir@atauni.edu.tr