traditional-medicine-2016_scientifictracks-workshop

Volume 5, Issue 2 (Suppl)

J Tradi Med Clin Natur

ISSN: JTMCN, an open access journal

Page 34

Notes:

Traditional Medicine 2016

September 14-16, 2016

conferenceseries

.com

September 14-16, 2016 Amsterdam, Netherlands

International Conference and Exhibition on

Traditional & Alternative Medicine

Histopathological and biochemical investigations of protective role of honey in rats with experimental

aflatoxicosis

Turan Yaman, Zabit Yener

and

Ismail Celik

Yuzuncu Yil University, Turkey

he aim of this study was to investigate the antioxidant properties and protective role of honey, considered a part of traditional

medicine, against carcinogen chemical aflatoxin (AF) exposure in rats, which were evaluated by histopathological changes in

liver and kidney, measuring level of serum marker enzymes, antioxidant defense systems, and lipid peroxidation content in liver,

erythrocyte, brain, kidney, heart and lungs. For this purpose, a total of eighteen healthy Sprague-Dawley rats were randomly allocated

into three experimental groups: A (Control), B (AF-treated) and C (AF+honey-treated). While rats in group A were fed with a diet

without AF, B, and C groups received 25 µg of AF/rat/day, where C group additionally received 1mL/kg of honey by gavage for 90

days. At the end of the 90-day experimental period, we found that the honey supplementation decreased the lipid peroxidation

and the levels of enzyme associated with liver damage, increased enzymatic and non-enzymatic antioxidants in the AF+honey-

treated rats. Hepatoprotective and nephroprotective effects of honey is further substantiated by showing almost normal histological

architecture in AF+honey-treated group, compared to degenerative changes in the liver and kidney of AF-treated rats. Additionally,

honey supplementation ameliorated antioxidant defense systems and lipid peroxidation content in other tissues of AF+honey-treated

rats. In conclusion, the present study indicates that honey has a hepatoprotective and nephroprotective effect in rats with experimental

aflatoxicosis due to its antioxidant activity.

Biography

Turan Yaman has completed his PhD from Yuzuncu Yil University School of Veterinary Medicine. He has published more than 4 papers in reputed journals.

Turan Yaman et al., J Tradi Med Clin Natur 2016, 5:2 (Suppl)