toxicology-congress-2018-scientifictracks-abstracts

12 / 32

Page 43
Notes:
conferenceseries.com
Volume 4 Toxicology: Open Access
ISSN: 2476-2067 Toxicology Congress 2018
March 12-14, 2018
March 12-14, 2018 Singapore
14th World Congress on
Toxicology and Pharmacology
Food functionalization and preservative activity of bioactive colorant prodigiosin
Regina Mary R1 , Arivizhivendhan K V2 and Sekaran G2
1Auxilium College, India
2Central Leather Research Institute, India
Prodigiosin (PG) is a natural red colored compound, widely used in
pharmacological and biological applications. This investigation focused on
nutraceutical and food functionalization potential of natural colorant PG was
compared synthetic food colorant erythrosine (ER). The antioxidant potential
of PG and ER was examined by DPPH and ABTS radical scavenging method.
The bactericidal efficiency of PG and ER were analyzed against six foodborne
pathogens. The food shelf life extant ability of PG and ER was analyzed using
meat extract powder (MEP) as a model food material. The PG (70.19 g/kg)
was biosynthesized from Serratia marcescens by solid state fermentation. The
scavenging activity of PG was calculated to be 99% and 99.9% were DPPH and
ABTS, respectively. ER shows DPPH, 81%; ABTS, 85.9% of radical scavenging
was achieved. The scavenging ability of PG was confirmed through UV-visible,
EPR, fluorescence spectrum and cyclic voltammetry analyses. The bactericidal
efficiency of PG against the selected foodborne pathogens exhibited significant inhibition on growth than the synthetic colorant
and the shelf life of the food was extended in the presence of PG containing food model. Hence, the PG may be used as food
colorant and thus significantly reduce the addition of synthetic colorant in food processing industry. This study will bring an
innovative approach on food additive for safe and sustainable food process.
Recent Publications
1. Arivizhivendhan K V, Mahesh M, Boopathy R, Patchaimurugan K, Regina Mary R, Sekaran G (2016) Synthesis of surface
modified iron oxides for the solvent free recovery of bacterial bioactive compound, prodigiosin and its algicidal activity.
The Journal of Physical Chemistry B; 120(36): 9685-9696.
2. Arivizhivendhan K V, Mahesh M, Boopathy R, Regina Mary R, Sekaran G (2016) A novel method for the extraction
of prodigiosin from bacterial fermenter integrated with sequential batch extraction reactor using magnetic iron oxide.
Process Biochemistry; 51(10): 1731-1737.
Biography
Regina Mary R has her passion in educating and empowering the rural young women. She has her expertise in the field of development of bioactive compounds
from microorganism for the biomedical application. Her contribution towards preparation of surface modification and bioactive compound conjugated nanoparticle
for the treatment of pathogens from water and food system with a molecular mechanistic explanation. She has built this model after years of experience in research,
evaluation, teaching and administration both in education institutions. She also has her unique contribution in the field of infection in gastrointestinal track and
respiratory track due to the foodborne pathogens and its treatment by probiotics for health benefits of young women.
Regina Mary R et al., Toxicol Open Access 2018, Volume 4
DOI: 10.4172/2476-2067-C1-005