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Structural Biology 2017

Day 3 September 20, 2017

Sessions:

Structural Biology in Cancer Research | Current Trends

Session Chair

Guo-Ping Zhou

Gordon Life Science Institute, USA

Session Co-Chair

Tzu-Ching Meng

Academia Sinica, Taiwan

Session Introduction

Title:

The NMR studies of the interaction between polysialic acid (polySA) and the PSTD peptide

in ST8Sia IV polysialytranseferase

Guo-Ping Zhou,

Gordon Life Science Institute, USA

Title:

Understanding differential selectivity of arrestins toward the phosphorylation state of

G-protein-coupled receptors

Ozge Sensoy,

Istanbul Medipol University, Turkey

Title:

Structural basis for the cooperative allosteric activation of the free fatty acid receptor

GPR40

Stephen M. Soisson,

Merck Research Laboratories, USA

Title:

Conformational dynamics revealed by ensemble cryo-EM

Andrei Korostelev,

UMass Medical School, USA

Title:

Structural basis for PTPN3-p38gamma complex involved in colon cancer progression

Tzu-Ching Meng,

Academia Sinica, Taiwan

Title:

Holliday junction resolvase GEN1 functions as a versatile DNA sensor and processor

Christian Biertümpfel,

Max Planck Institute of Biochemistry, Germany

Title:

Monitoring protein structural changes on a proteome-wide scale

Paola Picotti,

ETH Zurich, Switzerland

Title:

Slow domain reconfiguration causes power law kinetics in a two-state enzyme

Hagen Hofmann,

Weizmann Institute of Science, Israel

Title:

Structural and dynamic studies of DENV and ZIKV proteases and its insight into

inhibitor design

CongBao Kang,

Agency for Science, Technology and Research (A*STAR), Singapore

Title:

Assembly mechanism of foreign dsDNA-sensing inflammasomes

Jungsan Sohn,

Johns Hopkins University, USA

Title:

Functional divergence in protein families: A co-variation analysis

Marie Chabbert,

University of Angers, France

Title:

RNA-binding domain disorder modulates the RNA destabilizing activity in the TTP

family of proteins

Francesca Massi,

University of Massachusetts Medical School, USA

Title:

Role of conformational equilibrium in molecular recognition and capsid assembly: the

case of flavivirus capsid proteins

Fabio C. L. Almeida,

Federal University of Rio de Janeiro, Brazil

Title:

Integrative approaches for variant interpretation in coding regions

Sushant Kumar,

Yale University, USA

Title:

Generation of long acting therapies using glycosylated linkers

Abdulrahman Alshehri,

University of Sheffield, UK

Title:

Hydrogen bond interaction with trypanosomal adenosine kinase; ornithine

decarboxylase and triose phosphate isomerase could not be involved in the

antitrypanosomal activity of stigmasterol: An

in silico

study

Aminu Mohammed,

Ahmadu Bello University, Nigeria

Sessi I tr

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