skin-diseases-and-microbiology-2016

Volume 4, Issue 7(Suppl)

J Infect Dis Ther 2016

ISSN: 2332-0877, JIDT an open access journal

Page 54

Notes:

Skin Diseases & Microbiology 2016

October 03-05, 2016

conferenceseries

.com

October 03-05, 2016 Vancouver, Canada

International Conference on

Infectious Diseases, Diagnostic Microbiology &

Dermatologists Summit on Skin Infections

Combined treatment of mucocutaneous leishmaniasis after therapeutic failure: Case report

Ernesto Rojas Cabrera, Aleida Verduguez-Orellana, Marisol Cordova Rojas

and

Miguel Guzman-Rivero

Universidad Mayor de San Simon, Bolivia

Statement of the Problem:

The mucocutaneous leishmaniasis in Bolivia is caused by

L. braziliensis

. The clinical manifestations

of disease are lesions in mucosal membranes of oropharynx, larynx and nose. The first election drugs for treatment of this type of

leishmaniasis are the pentavalent antimony compounds although with variable efficacy. The absence of effect of antimony compounds

promotes the use of other drugs as second election. Nevertheless, in all cases there is the possibility of failure of therapy.

Methodology:

A combined treatment of antimony, miltefosine and itraconazole together with zinc as nutritional supplement in one

patient with the antecedent of therapeutic failure to different therapies was used.

Findings:

It was achieved the remission of disease at end of therapy as result of simultaneous lytic action of drugs used and also to the

restoration of immune response of patient by zinc.

Conclusion & Significance:

There was no relapse in patient after five years of intervention and he was considered clinically cured.

Biography

Ernesto Rojas Cabrera has expertise in Tropical Medicine. His work is focused mainly on American leishmaniasis.

Ernesto Rojas Cabrera et al., J Infect Dis Ther 2016, 4:7(Suppl)