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19th International Conference on
Obesity, Healthcare - Nutrition & Fitness
March 18 - 19, 2019 | New York, USA
Effect of oral ingestion
of low-molecular
collagen peptides
derived from skate
(raja kenojei) skin on
body fat in overweight
adults: a randomized,
double-blind, placebo-
controlled trial
Young Jin Tak
Pusan National University School of
Medicine, South Korea
Recent animal studies
found the potential that
collagen peptide derived from
skate skin have anti-obesity
effects through suppression
of fat accumulation and
regulation of lipid metabolism.
However, no studies have yet
been performed in human.
Here, this very first human
study randomized, placebo-
controlled, and double-blinded
was designed to investigate
the efficacy and tolerability of
skate skin collagen peptides
(SCP) for reduction of body fat
in overweight adults. Ninety
healthy volunteers (17 men)
aged 41.2 ± 10.4 years with
mean body mass index of 25.6
± 1.9 kg/m2 were assigned to
the intervention group (IG)
which received 2,000 mg of
SCP per day or to the control
group (CG) given placebo
for 12 weeks and 81 (90%)
participants completed the
study. Changes in body fat
were evaluated using dual
energy X-ray absorptiometry
as a primary efficacy endpoint.
After 12 weeks of trial, the
percentage of body fat and
body fat mass (kg) in IG were
found to be significantly better
than those of subjects in CG
(-1.2% vs. 2.7%, p=0.024 and
-1.2 kg vs. 0.3 kg, p=0.025).
Application of SCP was well
tolerated, and no notable
adverse effect was reported
from both groups. These
results suggest the beneficial
potential of SCP in reduction of
body fat in overweight adults.
JOURNAL OF OBESITY &WEIGHT LOSS THERAPY 2019, VOLUME: 4 | DOI: 10.4172/2165-7904-C2-094 ACCEPTED ABSTRACTS