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Notes:
Volume 7, Issue 3 (Suppl)
J Nutr Disorders Ther, an open access journal
ISSN: 2161-0509
Page 65
JOINT EVENT
&
July 27-29, 2017 Rome, Italy
Advances in Natural Medicines Nutraceuticals & Neurocognition
14
th
International Conference on Clinical Nutrition
13
th
International Congress on
Chemical constituents of agarwood
Jeong Hill Park
1
, Chi Thanh Ma
2
, Bo Wu
3
and
Sung Won Kwon
1
1
Seoul National University, Korea
2
University of Medicine and Pharmacy, Vietnam
3
China Medical University, Shenyang, China
T
he
Aquilaria
, consisting of 14 species of trees which belong to
Thymelaeaceae
, is mainly distributed in the rainforest of
Southeast Asia and India. Several species of this genus produce a dark aromatic resin in response to the insects, physical
cut, microbial infections, or chemical stimulation. The resin-deposited heartwood is known as agarwood, which has long been
used as an incense, sedative, analgesic and digestive herbal medicine in Asia. For the study on the chemical constituents and
its biological activity, we extracted agarwood chips from artificially inoculated
A. malaccensis
. 34 compounds were isolated
from the agarwood and their structures were elucidated using extensive spectroscopic methods which include NMR, Mass, IR
and CD spectroscopy. Most of them are sesquiterpenes or 2-(2-phenylethyl)-chromone compounds. Anti-proliferation activity
was tested for the isolated compounds. Compound I and J showed strong anti-proliferation activity against A-549 human lung
cancer cell line.
Biography
Jeong Hill Park has completed his PhD in 1987 from Seoul National University. He is a Professor at College of Pharmacy, Seoul National University since 1988.
His main research interest is the development of biologically active natural products including ginseng and agarwood. He published more than 250 research papers
and filed more than 20 patents.
hillpark@snu.ac.krJeong Hill Park et al., J Nutr Disorders Ther 2017, 7:3(Suppl)
DOI: 10.4172/2161-0509-C1-007