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Volume 6
Journal of Infectious Diseases & Therapy
ISSN: 2332-0877
Infection Prevention 2018
December 06-07, 2018
December 06-07, 2018 | Valencia, Spain
14
th
World Congress on
Infection Prevention and Control
Staphylococcus Aureus
infections in psoriasis plaques
Violeta Ionescu
a
, Andreea DINU
b
, Cristina CĂ
Ș
ARU
b
, Lucica SIMA
b
, Iuliana MIHAI
b
, CHIURCIU C.
b
and
PĂTRA
Ș
CU I.V.
a
a
Activeimmunity srl., Romania
b
Romvac Company S.A., Romania
Introduction:
Psoriasis is an inflamatory condition of the skin, of which chronic plaque psoriasis is the most common form
(1). Psoriasis is associated with alteration in the composition of skin bacterial biota (2).
Staphylococcus aureus
(3), group A
Streptococcus
and
Streptococcus pyogenes
are involved in psoriasis pathogenesis in genetically predisposed individuals (2,4-6).
S. aureus
colonization of lesional skin was associated with a significantly higher PASI (Psoriasis Area Severity Index) score,
even more evident when isolated strains were toxigenic (5,7).
Methodology:
This study aimed to investigate the prevalence of infections with pathogenic bacteria in psoriasis plaques.
For this purpose, randomly selected patients with plaque psoriasis were tested for bacterial infections in skin lesions using
conventional microbiological methods.
Results:
S. aureus
was cultivated in 75 of the 205 samples (36.6%), while methicillin-resistant
S. aureus
(MRSA) was identified
in 45 of 205 samples (21.9%). Other Gram–positive and Gram–negative cocci and bacilli were cultivated from psoriasis plaques:
Staphylococcus spp. (representing coagulase negative staphylococci – S.Co.N.) in 122 samples (59.5%), Bacillus/Paenibacillus
spp. in 58 samples (28.3%), Streptococcus spp. in 25 samples (12.2%), Enterobacteriaceae in 19 samples (9.3%) (of which
Klebsiella spp. was present in 4 samples, Enterococcus spp. in 3 samples, and Escherichia coli in 2 samples, representing 2%,
1.5% and 1%, respectively), Enterococcus spp. in 14 samples (6.8%), non-fermenting bacteria in 14 samples (6.8%) (including
Pseudomonas aeruginosa which was cultivated in 2 samples, 1% respectively), and Corynebacterium spp. in 7 samples (3.4%).
Conclusion:
Gram-positive bacteria were the most frequently found bacteria in psoriasis plaques. Of them, S. aureus was the
most prevalent, represented especially by MRSA strains. This study is intended as a warning about the necessity of evaluating
bacterial infections in psoriasis plaques, in order to clarify the connection between skin infection and onset or worsening of
psoriasis pathology.
Violeta Ionescu et al., J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C6-053
Figure 1:
Bacterial species and bacterial groups found in psoriasis plaques