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Journal of Infectious Diseases & Therapy |ISSN: 2332-0877 | Volume 6
June 25-26, 2018 | Vancouver, Canada
3
rd
International Conference on
2
nd
International Conference on
Infection, Disease Control and Prevention
Microbial Pathogenesis & Infectious Diseases
&
Risk factors of multi-drug resistant tuberculosis among pediatric patients: A retrospective cohort study
Raziel Vina S Espino
East Avenue Medical Center, Philippines
R
isk Factors of Multi-Drug Resistant Tuberculosis Among Pediatric Patients: A Retrospective Cohort Study: Determines the risk
factors of pediatric patients diagnosed with MDR-TB. Conducted in a tertiary hospital in Quezon City and Health Centers from
January 2011 to December 2016. A minimum cohort of 156 patients 0 – 18 years old, either bacteriologically – confirmed or clinically
diagnosed tuberculosis were included in the study. Patients whose significant data of their charts went missing were excluded in the
analysis. The following information were gathered a.) demographic profile: age, gender, nutritional status, socioeconomic status,
district b.) clinical profile, history of exposure, results of laboratories, clinical presentation, delay in treatment, previous treatment with
tuberculosis and outcome. 162 patients were analyzed, 12/162 had MDR – TB and 150/162 had Non MDR – TB. Results of univariate
analysis showed that age and symptoms of weight loss, back pain, night sweats and fever had significant association with MDR TB. Of
these factors, back pain (p=0.001; RR: 31.771; 95% CI: 3.801, 265.554) and fever (p=0.020; RR: 7.6587; 95% CI: 1.380, 42.494) were
independent factors significantly related with MDR TB. Age, weight loss, back pain, night sweats and fever had significant association
with MDR - TB. Larger sample population and a prospective study is recommended to assess the epidemiologic data and further
identify other possible risk factors for resistance.
J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C2-042