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conferenceseries.com
Euro Pathology 2018 | Hematologic Oncology 2018
June 20-21, 2018
Volume 8 Journal of Clinical & Experimental Pathology
ISSN : 2161-0681
15 th EUROPEAN PATHOLOGY CONGRESS
&
LEUKEMIA AND HEMATOLOGIC ONCOLOGY
June 20-21, 2018 | Paris, France
14th International Conference on
JOINT EVENT
Histopathological evaluation of 103 patients with rectal carcinoma
Nuri Emrah Goret
Canakkale State Hospital, Turkey
Objective: Colorectal carcinomas are the third most common carcinomas in men and the second most common carcinomas in
women worldwide. Pathological examination of rectum specimens requires special attention for correctly evaluating many
prognostically important factors. In this study, we aimed to present pathological results are 103 lower anterior resection (LAR) and
abdominoperineal resection (APR) specimens that we retrospectively evaluated over a six years of period.
Patients & Methods: One hundred three LAR and APR specimens were included in this study. Patients were evaluated in the
Istanbul Ekin Private Pathology Laboratory between January 2010 and January 2016.
Results: Of the 103 specimens, 14 (13.5%) were APR and 89 (86.4%) were LAR specimens. Fifty-six patients (54.4%) were males
and 47 patients (45.6%) were females. The mean age of the patients was 61.1 years. Twenty-three patients (22.3%) had undergone
neoadjuvant therapy. All surgical margins were negative in 100 specimens (97.1%), whereas a tumor was present in the distal
surgical margins in three specimens (2.9%). There was no lymph node metastasis in 59 patients (57.3%), whereas there was lymph
node metastasis in 44 patients (42.7%). Four (3.9%), 25 (24.3%), 58 (56.3%), 12 (11.6%) patients had stage T1, T2, T3, and T4
tumors, respectively, whereas 4 (3.9%) who had undergone neoadjuvant therapy had stage yT0 tumors. Eighty-six (83.6%), 7 (6.8%),
4 (3.9%), 1 (0.9%), 1 (0.9%), and 4 (3.9%) patients had adenocarcinoma, mucinous adenocarcinoma, intramucosal adenocarcinoma
in the setting of a high-grade tubulovillous adenoma, synchronous colon/prostate adenocarcinoma, malignant melanoma, and
adenocarcinoma diagnosed by the examination of colonoscopic biopsy specimens that showed complete regression with neoadjuvant
therapy, respectively.
Conclusion: When evaluating specimens from patients with colorectal carcinoma, pathological evaluation, which is one of the most
fundamental pillars, must be performed carefully and meticulously. Each pathological parameter should be evaluated carefully, and
clinicians and pathologists should evaluate these cases together.
Biography
Nuri Emrah Goret graduated from Medical School in 2006 and completed his Residency Training in General Surgery (2016). He is currently working at Canakkale
State Hospital as a Staff Surgeon since 2016.
Nuri Emrah Goret, J Clin Exp Pathol 2018, Volume 8
DOI: 10.4172/2161-0681-C1-045