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Volume 8, Issue 2 (Suppl) Chem Sci J 2017
ISSN: 2150-3494 CSJ, an open access journal Euro Chemistry 2017
May 11-13, 2017
May 11-13, 2017 Barcelona, Spain
4th European Chemistry Congress
Nirnay Samanta et al., Chem Sci J 2017, 8:2(Suppl)
Collective hydration dynamics in some amino acid solutions: A combined GHz-THz spectroscopic study
Nirnay Samanta1, Debasish Das Mahanta1, Samiran Choudhury2, Anjan Barman2 and Rajib Kumar Mitra 1
1,2S N Bose National Centre for Basic Sciences, India
Adetailed understanding of hydration of amino acids, the building units of protein, is a key step to realize the overall solvation
processes in proteins. In the present contribution we have made a combined GHz (0.2-50) to THz (0.3-2.0) experimental
spectroscopic study to investigate the dynamics of water at room temperature in presence of different amino acids (Glycine, L-Serine,
L-Lysine, L-Tryptophan, L-Arginine and L-Aspartic acid). The THz absorption coefficient, α(ν) of amino acids follows a trend defined
by their solvent accessible surface area (SASA). The imaginary and real dielectric constants obtained in GHz and THz regions are
fitted into multiple Debye model to obtain various relaxation times. The ~100 ps time scale obtained in the GHz frequency region is
attributed to the rotational motion of the amino acids. In the THz region we obtain ~8 ps and ~200 fs time scales which are related
to the cooperative dynamics of H-bond network and partial rotation or sudden jump of the under-coordinated water molecules.
These timescales are found to be dependent on the amino acid type and the cooperative motion if found to be dependent on both the
hydrophobic as well as the hydrophilic residue of amino acids.
Biography
Nirnay Samanta is a Senior Research Fellow (PhD scholar) in Physical Chemistry under the supervision of Dr. Rajib Kumar Mitra in S.N. Bose National Centre for
Basic Sciences, India. He is working on biophysical Chemistry and uses THz spectroscopy, GHz spectroscopy, steady state as well as time resolved fluorescence
spectroscopy etc. He has published 8 papers in reputed journals.