digital-pathology-2016_posters-accepted-abstracts

Notes:

Page 45

Digital Pathology & Pathologists 2016

December 05-06, 2016

Volume 6 Issue 5(Suppl)

J Clin Exp Pathol

ISSN: 2161-0681 JCEP, an open access journal

conferenceseries

.com

December 05-06, 2016 Madrid, Spain

World Digital Pathology & Pathologists Congress

Jolanda Nikolla et al., J Clin Exp Pathol 2016, 6:5(Suppl)

Demographic and clinical features in combined pulmonary fibrosis with emphysema syndrome patients

Jolanda Nikolla

and Hasan Hafizi

Hygeia Hospital, Albania

University Hospital “Shefqet Ndroqi”, Albania

Introduction:

Combined pulmonary fibrosis and emphysema (CPFE) has recently been recognized as a new entity. All

patients are heavy smokers or ex-smokers. High-resolution computed tomographic (HRCT) scan is 'the gold standard' for the

diagnosis. Prognosis is often poor and pulmonary hypertension is common. There is little information on clinical parameters

and predictors of mortality.

Aims & Objectives:

To identify clinical features and to study some demographic data in Combined Pulmonary Fibrosis and

Emphysema Syndrome (CPFE) patients.

Methods:

Medical records and HRCT scans from January 2010 through December 2015 were reviewed retrospectively at

our hospital. In total 25 patients had interstitial lung diseases (N=25) and from them 12 subjects with CPFE syndrome.

Clinical and demographic data were gathered, such as age, gender, smoking history, dyspnoea scale, clubbing, comorbidity,

cardiac ultrasound and pulmonary function data. Their values are presented as means±SDs or medians (range), depending on

distribution.

Results:

In CPFE, predominate smokers or ex smokers and all of them are males. Mean age is 69.3±7.1.Mean UPY (Unit Pack

Year) values for smoking status is 40.7±15.6. The mean time from symptoms to diagnosis was 2.08±0.9. The mean partial

pressure of oxygen (PaO

) in CPFE patients was 61.5±9.4 mmHg.

Conclusions:

Patients with CPFE syndrome are characterized by dyspnoea often severe, preserved lung volumes, severely

impaired gas exchanges. They are severely ill and needs more for oxygen therapy.