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Digital Pathology & Pathologists 2016
December 05-06, 2016
Volume 6 Issue 5(Suppl) J Clin Exp Pathol
ISSN: 2161-0681 JCEP, an open access journal
conferenceseries .com
December 05-06, 2016 Madrid, Spain
9th World Digital Pathology & Pathologists Congress
Ahmet Aydogan, J Clin Exp Pathol 2016, 6:5(Suppl)
Immunohistochemical evaluation of Bcl 2, caspase 3, 8 and 9 expressions in canine mammary carcinomas
Ahmet Aydogan
Cukurova University, Turkey
The present study investigated immunohistochemical expression of bcl 2, caspase 3, 8 and 9 in the canine mammary
carcinomas. We collected 65 paraffin-embedded canine mammary tumor tissue samples and were used as material. These
samples were examined histopathologically. After this, routine streptavidin-biotin-peroxidase technique was performed. Data
were statistically analyzed using Cronbach’s alpha, Kruskal–Wallis and Bonn-Ferroni-Dunn tests. Microscopically, 17 of the
cases were diagnosed as tubulopapillary carcinoma, 31 of the cases were diagnosed as complex carcinoma and 17 of the cases
were diagnosed as carcinosarcoma. Differences in immunohistochemical expression of bcl-2 was found statistically significant
according to tumor types (P<0.01). The other parameters (caspase-3, -8 and -9) were not found statistically significant (P>0.05).
In addition, expression of bcl-2 was detected statistically significant in carcinosarcoma cases (P<0.01).
Biography
Ahmet Aydogan has completed his PhD from Adnan Menderes University, Turkey and Post-doctoral studies from Mehmet Akif Ersoy University, Turkey. He is
currently an Associate Professor at the Cukurova University, Faculty of Veterinary Medicine, Department of Pathology, Adana, Turkey. He has published more than
30 papers in reputed journals and has been serving as a Reviewer of repute.