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Digital Pathology & Pathologists 2016
December 05-06, 2016
Volume 6 Issue 5(Suppl) J Clin Exp Pathol
ISSN: 2161-0681 JCEP, an open access journal
conferenceseries .com
December 05-06, 2016 Madrid, Spain
9th World Digital Pathology & Pathologists Congress
Mehmet Haligur, J Clin Exp Pathol 2016, 6:5(Suppl)
Evaluation of caspases expression in brain lesions of sheep naturally infected with listeriosis
Mehmet Haligur
Cukurova University, Turkey
Background&Aim: Listeriosis is a disease that can cause serious economic losses in sheep. Infectionwith Listeriamonocytogenes
can lead to many syndromes in animals. The aim of this study was evaluation of caspase expressions in encephalitic listeriosis.
Methods & Materials: A total of 20 sheep brains were histopathologically and immunohistochemically examined.
Histopathologically,microabscesses,perivascularandmeningealcellinfiltrationswerecommonlyseen.Immunohistochemically,
prominent positive reactions were detected in the caudal brain for caspases (CSPs) -3, -7, and -9.
Results: With regard to cell-specific labeling, necrotic neurons were positive for CSP-3 and -9, Purkinje cells were positive
for CSP-3 and -7, CSP-3 was found in neutrophil leukocytes, and CSP-9 was observed in lymphocytes. In addition, only the
ependymal cells exhibited immunopositivity for CSP-9.
Conclusion: Collectively, our data from naturally infected sheep indicate that CSP-3, -7 and -9 may play roles in encephalitic
listeriosis pathogenesis.
Biography
Mehmet Haligur has completed his PhD from Ankara University, Turkey and Post-doctoral studies from Akdeniz University and Mehmet Akif Ersoy University,
Turkey. He is currently an Associate Professor at the Cukurova University, Faculty of Veterinary Medicine, Department of Pathology, Adana, Turkey. He has
published more than 40 papers in reputed journals and has been serving as a Reviewer of repute.