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Clinical Gastroenterology 2016

October 03-05, 2016

Volume 6, Issue 6(Suppl)

J Gastrointest Dig Syst

ISSN:2161-069X JGDS, an open access journal

conferenceseries

.com

October 03-05, 2016 Toronto, Canada

8

th

International Conference on

Clinical Gastroenterology & Hepatology

J Gastrointest Dig Syst 2016, 6:6(Suppl)

http://dx.doi.org/10.4172/2161-069X.C1.041

Whole gut ischemia: Diagnostic and management challenges

Oumer Jemal Yenus

Bahir Dar University, Ethiopia

G

ut ischemia is not a common condition. It occurs in patients who are on certain medications or those who have cardiac

abnormalities. It affects largely on the major vessels supplying part of the gut and that part will be ischemic. Here, we

present a case of whole gut ischemia where all parts of the gut from the stomach to the rectum are involved by the insult which

is a rare presentation. All major vessels are not palpable. Its presentation, diagnosis and management will be discussed in detail.

oumerjemal@gmail.com

Body mass index may predict the long-term outcomes of advanced gastric cancer

Beom Jin Kim, Jae G Kim, Kyung Cheon Chi, Jung Min Park, Mi Kyoung Kim and In Kyu Hwang

Chung-Ang University, South Korea

Objectives:

Radical gastrectomy followedby adjuvant chemotherapy for advanced gastric cancer brings about serious nutritional

impairment. Recent studies have shown an association between body mass index (BMI) and perioperative outcomes of gastric

cancer. However, little is known about the association between BMI and long-term outcomes of advanced gastric cancer. Our

study evaluated the clinical impact of BMI on the long-term outcomes of gastric cancer staged at II and III, treated by radical

gastrectomy followed by adjuvant chemotherapy.

Methods:

We analyzed a total of 211 cases of advanced gastric cancer stage II and III between January 2005 and December

2010 at Chung-Ang University Hospital. The patients were divided into 4 groups according to BMI; underweight, normal,

overweight and obese. In addition, they were divided into two groups (BMI-High vs. BMI-Low). We assessed age, sex, tumor

location, lymph node involvement, operation method, initial cancer stage, recurrence, and survival (overall survival and

disease free survival) between two groups.

Results:

We classified them into 4 groups according to BMI; underweight, normal, overweight, and obese. There was no

difference in overall survival between normal, overweight, and obese group. However, there was significant difference between

underweight group and the other groups. As for disease free survival, similar findings were observed. Among 211 patients,

154 patients (72.9%) were included in BMI-L (body mass index <25), whereas 57 patients (27.1%) in BMI-H (body mass index

≥25). There was no difference in age, sex, tumor location, stage, lymph node involvement, operation method, recurrence, and

cancer-related death between two groups. When classified into 4 groups as stage II in BMI-H, stage II in BMI-L, stage III in

BMI-H, and stage III in BMI-L, overall survival showed significant difference in stage, however, no difference between BMI-H

and BMI-L was observed. Disease free survival showed no significant difference in stage and BMI, especially, no significant

difference between stage II in BMI-L and stage III in BMI-H.

Conclusion:

Our findings suggest that preoperative BMI may predict the long term outcomes of advanced gastric cancer after

radical surgery and chemotherapy.

kimbj@cau.ac.kr