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Clinical Gastroenterology 2016
October 03-05, 2016
Volume 6, Issue 6(Suppl) J Gastrointest Dig Syst
ISSN:2161-069X JGDS, an open access journal
conferenceseries .com
October 03-05, 2016 Toronto, Canada
8th International Conference on
Clinical Gastroenterology & Hepatology
Marital status and survival in patients with primary liver cancer
Xing-kang He, Zheng-hua Lin, Yun Qian and Lei-min Sun
Zhejiang University Medical School, China
Objective: Marital status is viewed as an independent prognostic factor for survival in various cancer types. However, its role
in primary liver cancer hasn’t been thoroughly explored. In this study, we aimed to investigate the impact of marital status on
survival outcomes among liver cancer patients.
Methods: We used the surveillance, epidemiology and end results (SEER) database to identify 40,809 patients diagnosed
with primary liver cancer between 2004 and 2012. Kaplan-Meier analysis and Cox regression were performed to identify the
influence of diverse marital status on overall and liver cancer-specific survival.
Results: We finally identified 40,809 eligible liver cancer patients between 2004 and 2012, including 21,939 (53.8%) patients
were married at diagnosis and 18,870 (46.2%) was unmarried (including the divorced/separated, the widowed, and the single).
Married patients had better overall and cause-specific survival outcomes compared with patients who were divorced/separated,
widowed, single, respectively. The benefit associated with marriage still persisted even after adjusted for other confounders.
Widowed individuals were at greater risk of overall and cancer-specificmortality compared to other groups. Similar associations
were observed in subgroup analyses according to SEER stage.
Conclusions: Our results indicated that marital status was a prognostic factor for better survival outcomes in liver cancer
patients. We speculated that social support may contribute better survival outcomes, especial for the widowed. More social
supports and care should be provided for unmarried patients in our clinic practice.
J Gastrointest Dig Syst 2016, 6:6(Suppl)
Association between clinical sign and colorectal mucosal lesion severity in patients with inflammatory
bowel disease
Inggar Armytasari
Gadjah Mada University, Indonesia
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease in gastrointestinal tract. The clinical signs of IBD
include chronic diarrhea, with or without mucous and/or with or without rectal bleeding. It hasn’t surely been known that
there is a positive correlation between clinical sign and colorectal mucosal lesion severity in the IBD patients. This study
aims to determine the relationship between clinical sign in inflammatory bowel disease patients with the varying colorectal
mucosal lesion. The study was conducted in a retrospective cross section using the medical record data from both inpatient
and outpatient with IBD at the Sardjito General Hospital from January 2012 until July 2014. From 65 data (42 men, 23 women
and age 18 to 97 years old (49.94±18.25)), there was an insignificant weak positive correlation between clinical signs and lesion
severity in IBD (p=0.0916, r=0.211), also in proctitis (p=0.1543, r=0.2876). Meanwhile, in left-sided colitis, the correlation is
insignificant and has a very weak positive correlation (p=0.9518, r=0.0125). The only significant and stronger correlation is
the correlation between rectal bleeding and lesion severity in the proctitis patients with p=0.0053 and r=0.5310. So, it can be
concluded that there was an insignificant weak positive correlation between clinical signs and lesion severity in IBD, except for
the proctitis, where the correlation between rectal bleeding and lesion severity was rather high. From this conclusion we can
assume that clinical signs only, cannot reflect the disease severity of IBD, with the exception of proctitis where the severity of
rectal bleeding can also depict the severity of the lesion.