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Journal of Gastrointestinal & Digestive System | ISSN: 2161-069X | Volume: 8

October 29-30, 2018 | San Francisco, USA

International Conference on

Gastrointestinal Cancer and Therapeutics

World Congress on

Digestive & Metabolic Diseases

Annual Congress on

Cancer Science and Targeted Therapies

Association of glycated hemoglobin and bodymass index with chronic kidney disease among type 2 diabetic

patients in North-eastern Thailand

Sojib Bin Zaman

1,2

Charity University Medicine Berlin, Germany

Khon Kae University, Thailand

Background:

The prevalence of chronic kidney disease (CKD) amidst Thai adult type 2 diabetes mellitus (T2DM) patients is quite

high. Uncontrolled DM and obesity can play a role to initiate this renal vascular complication. Glycated hemoglobin (HbA1c) a well-

known valid biomarker to estimate glycemic control. However, it is not clear whether HbA1c and body mass index (BMI) with other

conventional indicators can act as a reliable determinant to predict CKD.

Methods:

A diabetic registry was used to collect 4042 participants from a large district hospital in the Northeast of Thailand. CKD

was reported as estimated glomerular filtration rate; eGFR<60 ml/min/1.73m2. Using STATA, multiple logistic regression analysis

was performed to report adjusted odds ratio.

Results:

More than one-fifth of T2DM patients (887, 21.9%), were found with CKD. The majority of the participants were in the poor

glycemic state (82%), and 43% of them were overweight. HbA1c was found not to be a reliable indicator for CKD. Age, hypertension,

microalbuminuria, and triglyceride were considered to be the implied risk factors besides HbA1c in this study. Also, BMI is seemed

to decrease in the course of developing CKD.

Conclusion:

It appears to the presence or lack of generally accepted indicators for detecting CKD in T2DM patients. The lower values

of HbA1c and BMI for high-risk CKD patients might be explained by the fact that CKD patients usually develop anemia and their

nutritional status can declines. Both the contemporary guidelines of HbA1c and BMI need to be modified in consideration of CKD

patients.

J Gastrointest Dig Syst 2018, Volume 8

DOI: 10.4172/2161-069X-C8-086