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conferenceseries
.com
Volume 8, Issue 6 (Suppl)
J Bioremediat Biodegrad, an open access journal
ISSN:2155-6199
Biopolymers & Bioplastics 2017
October 19-20, 2017
October 19-20, 2017 San Francisco, USA
7
th
International Conference and Exhibition on
Biopolymers and Bioplastics
Enantiomeric separation of DL-propranolol using cellulose membrane
Yuan Liming
and
Ma Chao
Yunnan Normal University, P.R. China
S
ince cellulose possesses multichiral carbon atoms in its molecular structure unit, an enantioselective membrane was prepared using
cellulose as the membrane material. The flux and permselective properties of a membrane were studied using DL-propranolol
racemate as the feed solution. In order to optimize the permselective properties of the cellulose membrane, the influences of different
parameters such as operating pressure and feed concentration of racemates had been studied. The top surface and cross-section
morphology of the resulting membrane were examined using scanning electron microscopy. An optical resolution of over 55%
enantiomeric excess was achieved when the enantioselective membrane was prepared with 8.1wt% cellulose and 8.1wt% LiCl in the
casting solution of N,N-dimethyl acetamide. This work indicates that the enantioselective cellulose membrane could soon become
very attractive for industrial uses. The work is supported by National Natural Science Foundation (No. 21127012, 21675141) of China.
Biography
Li-Ming Yuan was born in Chongqing, China, 1961. He received his Ph.D. from Beijing Institute of Technology (1997, China) and then spent about two years (2002-
2004) at the Nagoya University (Japan) as a postdoctoral fellow (JSPS) with Prof. Y. Okamoto. In 1998 he was promoted to professor in Yunnan Normal University
of China. His current research interests focus on the enantioseparations by chromatography, polymeric membrane and extraction.
yuan_limingpd@126.comYuan Liming et al., J Bioremediat Biodegrad 2017, 8:6 (Suppl)
DOI: 10.4172/2155-6199-C1-012