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Bio Summit & Molecular Biology 2016
October 10-12, 2016
Volume 6, Issue 6(Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
conferenceseries .com
October 10-12, 2016 Dubai, UAE
2nd World Congress on
Bio Summit & Molecular Biology Expo
Mohamed Mostafa Shokry, J Biotechnol Biomater 2016, 6:6(Suppl)
Potential of camel-derived hemoglobin oxygen carriers as a blood substitute
Mohamed Mostafa Shokry
Cairo University, Egypt
The quest for producing a blood substitute is the result of an incessant demand not only for routine surgery and accidents but
also in cases of mass civilian casualties during natural disasters, terrorism and wars. The risks of allogenic blood transfusion
are multiple and include infections transmission (HIV and Hepatitis B and C), delayed postoperative healing, transfusion
reactions, transfusion-related lung injury, immunodilution and potential risk of cancer recurrence. Blood primarily functions
transport oxygen to tissues. This function performed by hemoglobin (Hb), a protein encapsulated inside the red blood cells
(RBCs) that is capable of binding and releasing oxygen. Hb-based oxygen carriers HBOCs are being developed as substitute
to replace the oxygen-carrying functions of erythrocytes and thereby lessen the demand of donor blood during surgery and
trauma situations. Artificial blood substitutes present several advantages over the use of donor blood for blood transfusions
because they have no antigenic blood groups on their surface, no possibility for transmitting infections; they have a longer
storage lifetime and are cost efficient. Bovine and human Hb forms the bases of many different types of (HBOCs) ranging from
chemically modified Hbs, including cross-linked, polymerized, polymerized conjugated to particle encapsulated.
Biography
Mohamed Mostafa Shokry has completed his PhD from Cairo University, Egypt. He is a Professor Emeritus of Veterinary Surgery & Anesthesia in Cairo University,
Egypt. He has published more than 75 papers in scientific journals and has published many library books.