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Bio Summit & Molecular Biology 2016
October 10-12, 2016
Volume 6, Issue 6(Suppl) J Biotechnol Biomater
ISSN: 2155-952X JBTBM, an open access journal
conferenceseries .com
October 10-12, 2016 Dubai, UAE
2nd World Congress on
Bio Summit & Molecular Biology Expo
Bassem M Raafat, J Biotechnol Biomater 2016, 6:6(Suppl)
Hemoglobin derivatives concentration enhancement after usage of magnetic treated water (MTW)
through heavy metal chelation therapy
Bassem M Raafat
Taif University, Saudi Arabia
S afe drinking water is essential to humans and other life forms even though it provides no calories or organic nutrients.
Access to safe drinking water has improved over the last decades in almost every part of the world but approximately one
billion people still lack access to safe water and over 2.5 billion lack accesses to adequate sanitation. The aim of this work was
to evaluate the enhancement of the hemoglobin different derivatives concentration when normal drinking water replaced by
magnetic treated water (MTW) through a heavy metal chelation process. 41 male rats were included. Control group (G1),
animals did not subject to lead poisoning and drink normal water. Second group (G2) whose did not subject to lead but drink
MTW. Third group (G3) received lead ions for 21 days and drink normal water. Fourth group (G4) those received lead ions
concomitant with chelation therapy of dimercaptosuccinic acid (DMSA) and drink normal water. Fifth group (G5) those
subjected to lead ions concomitant with chelation therapy of dimercaptosuccinic acid (DMSA) and drink MTW. The rate by
which hemoglobin undergo oxidation, hemoglobin normal and abnormal derivatives concentration, superoxide dismutase
and glutathione peroxidation activity and electrical conductivity of hemoglobin were measured. Results showed a significant
enhancement in normal hemoglobin derivatives concomitant with reduction in abnormal derivatives. Usage of MTW revealed
increase in antioxidants activity. In conclusion, it is safe to say that MTW improved the chelation process.
Biography
Bassem M Raafat has completed his PhD from Cairo University and Postdoctoral studies from the National Research Center, Egypt. He is the Vice Dean of Applied
Medical Science College, Taif University, Saudi Arabia. He is the Head of E-Learning Unit and Scientific Research and Higher Education. He is the Coordinator
of The Genetic Engineering and Biotechnology Division in NRC. He has published more than 42 papers in reputed journals and has been serving as an Editorial
Board Member for more than 15 international well ranked journals.