livestock-nutrition-2016_scientifictracks-workshop

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Volume 4, Issue 2 J Fisheries Livest Prod
ISSN: 2332-2608 JFLP, an open access journal
Page 33
Notes:
Livestock Nutrition 2016
July 21-22, 2016
conferenceseries.com
July 21-22, 2016 Brisbane, Australia
2nd International Conference on
Livestock Nutrition
Concentration and distribution of sialic acid in sow milk during lactation
Marefa Jahan, P Wynn and B Wang
Charles Sturt University, Australia
Sialic acids (Sia), a family of 9-carbon acidic sugar molecules are keymonosaccharide units of brain gangliosides and glycoproteins and
a major component of sialylated glycotope in human milk. Human milk Sia has been proposed as a bioactive compound promoting
immune function, gut maturation and neurodevelopment of the newborn. Porcine milk however has received little attention. The
aims of the present study were to quantify and compare the levels of N-acetyl neuraminic acid (Neu5Ac), N-glycolylneuraminic
acid (Neu5Gc) and keto deoxy nonulpsonic acid (KDN) in oligosaccharide, glycoprotein and glycolipid in sow milk during course
of lactation. Milk samples from 22 sows were collected by manual expression on 3 occasions, day 1 (colostrum), day 3 (transition
milk) and day 15-21 (mature milk) respectively. The concentrations of Neu5Ac, Neu5Gc and KDN were analyzed using UHPLC.
The results showed that sow milk contained significant amounts of Sia with the highest concentration found in colostrum (1238.50
mg/L) followed by transition milk (778.32 mg/L) and then mature milk (347.21 mg/L). Most of the Sia in sow milk was conjugated to
glycoproteins (41-46%), free oligosaccharides (31-42%) and then glycolipid (12-28%) throughout the course of lactation. Neu5Ac was
the major form of Sia (93-96%) and then Neu5Gc (3-6%), KDN however contained as little as 1-2%. This distribution was common
to each milk fraction and to each time point in lactation. In conclusion, porcine milk contains a rich source of sialylated glycan in
the forms of glycoproteins, free oligosaccharides and glycolipids. The high concentrations of Sia in porcine milk suggest that Sia is an
important nutrient that may contribute to the optimization of immune function, neurodevelopment and growth and development
of piglets.
Biography
Marefa Jahan is currently a PhD student in School of Animal and Veterinary Sciences, Charles Sturt University, Australia. She is working for better health and
nutrition of the livestock.
Marefa Jahan et al., J Fisheries Livest Prod 2016, 4:2 (Suppl)