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conferenceseries
.com
10
th
International Conference on
February 22-23, 2018 | Paris, France
Vascular Dementia
Volume 8
Journal of Alzheimers Disease & Parkinsonism
ISSN: 2161-0460
Vascular Dementia 2018
February 22-23, 2018
A new direction for Alzheimer’s research
James D Weinstein
Marshall University, USA
A
lthough billions of dollars have been spent for research on Alzheimer’s disease (AD), little progress has been made in finding
a therapy which stops the progressive dementia characteristic of the disease. Numerous drugs, having failed over years of
research suggests the need for re-evaluation of how the research is now being done. To that end, three changes in current AD research
methodology are offered and these changes are absolutely necessary to provide the means to find an effective treatment for the
disease. First, AD is a disease of four etiologies rather than from a single primary cause. These four should be treated simultaneously
for an effective therapy. Second, AD drug testing is wasting much time effort and money by aiming for a statistical verification of
the slowing of dementia. The end point should be the complete cessation of progressive dementia, and testing should begin with
small cohorts. Third, combination therapies with drugs currently available, used off label, ought to be tried. One example of such a
combination is reviewed.
Biography
James D Weinstein has completed his MD in 1964 from University of Pennsylvania and his Internship from New England Center Hospital in Boston in 1965. He has
worked as a Neurosurgeon for more than 40 years in New Jersey and West Virginia. He has published more than 25 papers in reputed journals.
jweinstein3438@gmail.comJames D Weinstein, J Alzheimers Dis Parkinsonism 2018, Volume 8
DOI: 10.4172/2161-0460-C1-036