2 / 8
Volume 6
Journal of Infectious Diseases & Therapy
Tropical & Bacterial Diseases 2018
December 05-06, 2018
Page 52
Notes:
conference
series
.com
Annual Conference on
Bacterial, Viral and Infectious Diseases
&
Neglected Tropical Diseases Congress: The Future Challenges
December 05-06, 2018 Dubai, UAE
Correlation of dengue serology with disease severity
Sachin Damke
1,2
1
Jawaharlal Nehru Medical College, India
2
Datta Meghe Institute of Medical Sciences, India
Background & Objective:
Dengue fever is one of the most common arboviral mediated outbreaks. The disease carries high morbidity
and mortality. The spectrum ranges from mild self-limiting illness to severe fatal disease. This study was designed to correlate the
dengue serology with the disease.
Methods:
Prospective observational study was undertaken among pediatric patients in a rural tertiary care hospital. The study
conducted over a period of 4 years. In patients suspected as dengue NS1 antigen, IgM and IgG for dengue were sent and those who
were positive for at least one of the three were included in the study.
Results:
In the study, 234 patients studied, majority were males (68%). In the presenting symptom, fever was the most common
symptom (100%) followed by headache (86%), myalgia (84%). Edema was observed in 19% while rash in 13%. According to the
WHO criteria 174 (74%) were classified as non-severe dengue while 60 (26%) as severe dengue. Thrombocytopenia was seen in 97%
of patients. The complications of dengue observed in our study were hemorrhagic manifestations (26%), shock (33%), ARDS (8%)
and CNS involvement (5%). Mortality rate was 8.97%. In the children classified as severe dengue only 5 (2%) children had only NS1
positive, 21 (9%) were positive for IgM, 11 (5%) for IgG and 23 (10%) for both IgG and IgM.
Biography
Sachin Damke has completed MBBS in 2001 and MD pediatrics in 2006. He is working in a medical college from last 10 years.
buntydamke@gmail.comSachin Damke, J Infect Dis Ther 2018, Volume 6
DOI: 10.4172/2332-0877-C7-057