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Volume 7 Traditional and Restorative Medicine & Neuropharmacology 2018 | August 27-29, 2018
Journal of Traditional Medicine & Clinical Naturopathy | ISSN : 2573-4555
conferenceseries LLC Ltd
JOINT EVENT
Global Summit on
Traditional & Restorative Medicine
10 th World Congress on
Neuropharmacology
Page 29
August 27-29, 2018 | Paris, France
Potential application of the West African frankincense (Boswellia dalzielii
Hutch) for drug and perfumery products
Boswellia dalzielii is the West African species of the frankincense producing genus (B.
carterii, B. frereana and B. serrata are the more popular congeners). Its ethnobotanical
uses include the treatment of rheumatism, venereal diseases and gastro-intestinal disorders
among others. Scientific investigations were carried out to evaluate the biological
properties relevant to their ethnomedical uses and to better understand the chemistry of
the plant. This is with a view to identify possible applications for medicinal, cosmetic and
industrial purposes. The stem bark was subjected to solvent extraction and activity-directed
fractionation to isolate bioactive compounds. The isolated compounds were characterized
using joint spectroscopic techniques, including 2-D NMR and mass spectrometry. The
gum resin was steam-distilled to obtain volatile oil, which was analyzed by GC-MS.
Another portion of gum resin was also extracted by organic solvent and fractionated by
column chromatography. From the results obtained, the antimicrobial/antioxidant activity
of the stem bark was accounted by isolated compounds – protocatechuic acid, gallic acid
and ethyl gallate with minor contribution from a novel stilbene glycoside and a cembrane
diterpenoid (incensole). The extracts also demonstrated antifungal, anti-inflammatory,
cytotoxic and hypoglycemic effects. The gum resin (frankincense) showed anti-
inflammatory activity and yielded volatile oil consisting of mainly monoterpenes (fragrant
essence). The extract of gum resin yielded incensole and 3-O-acetyl-11-keto-boswellic
acid (AKBA). The spectrum of observed biological activities justifies the ethnomedical
uses and suggests great potential for further drug development. The essential oil can be
employed in perfumery products and in related industry.
Biography
Taiwo Emmanuel Alemika has completed his PhD and is a Professor at the Department of Pharmaceutical
Chemistry, University of Jos, Nigeria. He is the Deputy Centre Leader of the World Bank sponsored African
Centre for Phytomedicine Research & Development (ACEPRD) at the University of Jos. He has published
more than 35 papers in peer-reviewed journals.
Taiwo Emmanuel Alemika et al., J Tradit Med Clin Natur 2018, Volume:7
DOI: 10.4172/2573-4555-C1-002
Taiwo Emmanuel Alemika
University of Jos, Nigeria
Co-Authors
Olalekan S Ojerinde,
Opeyemi Balogun and Yves S Kafuti
University of Jos, Nigeria