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Volume 7, Issue 4 (Suppl)

Clin Exp Pharmacol

ISSN: 2161-1459 CPECR, an open access journal

Pharmacology Congress 2017

July 24-25, 2017

July 24-25, 2017 Melbourne, Australia

8

th

World Congress on

Pharmacology and Toxicology

Surface electromyography analysis of blepharoptosis correction by transconjunctival incisions

Lung-Chen Tu

Taiwan

U

pper eyelid movement depends on the antagonisticactions of orbicularis oculi muscle and levatoraponeurosis.

Blepharoptosis is an abnormal droopingof upper eyelid margin with the eye in primaryposition of gaze. Transconjunctival

incisions forupper eyelid ptosis correction have been a welldevelopedtechnique. Conventional prognosishowever depends on

clinical observations and lacksof quantitatively analysis for the eyelid musclecontrolling. This study examines the possibility

ofusing the assessments of temporal correlation insurface electromyography (SEMG) as a quantitativedescrip- tion for the

change of muscle controllingafter operation. Eyelid SEMG was measured frompatients with blepharoptosis preoperatively

andpostoperatively, as well as, for comparative study,from young and aged normal subjects. The data wereanalyzed using the

detrended fluctuation analysismethod. The average DFA a index values for all ofthe eyes from the young and aged normal

groups andthe patient group from before and after the operationsare plotted in Fig. 7. The results show that thetemporal

correlation of the SEMG signals can becharacterized by two indices asso- ciated with thecorrelation properties in short and long

time scalesdemarcated at 3 ms, corresponding to the time scaleof neural response. Aging causes degradation of thecorrelation

properties at both time scales, and patientgroup likely possess more serious correlationdegradation in long-time regime which

wasimproved moderately by the ptosis corrections. Wepropose that the temporal correlation in SEMGsignals may be regarded

as an indicator forevaluating the performance of eyelid musclecontrolling in postoperative recovery.

lawrencetu99@gmail.com

Clin Exp Pharmacol 2017, 7:4 (Suppl)

DOI: 10.4172/2161-1459-C1-020