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.com

Volume 6, Issue 5 (Suppl)

J Pain Relief, an open access journal

ISSN: 2167-0846

Pain Management 2017

October 05-06, 2017

5

th

International Conference and Exhibition on

October 05-06, 2017 London, UK

Pain Research And Management

Subclinical atherosclerosis and peripheral vascular disease in systemic sclerosis patients: Relation to

potential risk factors

Neveen A Farag, Eman M El Serougy, Seham A Metawee

and

Hatem S El Azizi

Cairo University, Egypt

Objective:

To measure the extent of subclinical atherosclerosis in patients with systemic sclerosis, and to evaluate any potential

vascular risk factors including blood sugar, blood pressure, adverse lipid profile, and steroids and other medications usage.

Methods:

Thirty systemic sclerosis (SSc) patients and twenty healthy individuals were included as a control in this study.

Non-invasive vascular tests including; carotid duplex scanning measuring internal and common carotid arteries intima-media

thickness (IMT), and ankle brachial pressure index (ABPI) were performed. Traditional vascular risk factors as blood pressure,

blood sugar, lipid profiles, steroids usage and other immunosuppressive medications were assessed.

Results:

Mean IMT of carotid arteries was higher in SSc patients when compared with control group. Carotid plaques were

found in 4 SSc patients. Mean IMT was correlated positively with patients’ age, disease duration, systolic blood pressure, and

dyslipidemia. ABPI was significantly lower in SSc patients when compared with controls. No difference was found between

limited and diffuse disease subtypes in mean IMT, nor in mean ABPI. There was not any positive correlation between mean

IMT and cumulative steroid dose or any other immunosuppressive intake.

Conclusion:

Increased risk of subclinical vascular disease in SSc patients. Systolic blood pressure, adverse lipid profile, long

disease duration and older age of patients were of the potential risk factors in SSc.

neveenayoub@yahoo.com

J Pain Relief 2017, 6:5(Suppl)

DOI: 10.4172/2167-0846-C1-015