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Volume 2, Issue 2 (Suppl)

Optom open access

ISSN: 2476-2075 OMOA, an open access journal

Ophthalmologists 2017

September 25-26, 2017

September 25-26, 2017 Dubai, UAE

11

th

Global

Ophthalmologists Annual Meeting

Management of resistant keratitis in a sample of patients attending Cairo University Hospital

Hala El Mofty

Cario University, Egypt

Purpose:

To apply a step wise evaluation and a treatment plan for patients with resistant keratitis.

Patients & Methods:

In this prospective study, laboratory diagnosis and treatment outcome were assessed in 40 patients with

clinical diagnosis of resistant keratitis that failed to improve by conventional medical treatment. Each patient was evaluated by

clinical examination, ultrasound as well as specimen collection from the affected eye for laboratory evaluation. Sterile swabs,

scraping, biopsy or contact lens, specimens were inoculated directly onto blood agar, chocolate agar and Sabouraud dextrose

agar (SDA) and smeared onto two slides-one for Gram stain and the other for 10% KOH wet preparation. Direct microscopy

and culture methods were used for diagnosis of bacterial and fungal keratitis.

Results:

14/40 was diagnosed as bacterial keratitis, 16 patients were diagnosed as fungal keratitis with (fungal/bacterial

ratio was 1.14/1). Six patients had mixed bacterial and fungal infection. Trauma was the most important predisposing factor

(42.5%).

Pseudomonas

was the most frequent bacterial isolate (20%) while

Aspergillus

was the most frequent fungal isolate

(31.8%). Medical therapy failed in 16% of cases that necessitated surgical intervention. Keratitis healed without complications

in 87.5%; however, complications occurred in 12.5% of cases. No statistically significant difference was observed when we

compared occurrence of complications between fungal keratitis and bacterial keratitis cases (p>0.05).There was an overall

success rate without complications in 84% of cases treated medically and 93.3% of cases treated by combined medical and

surgical treatment.

Conclusions:

Understanding the cause of resistant keratitis and using a planned protocol for management improves the

outcome and decrease the need for urgent penetrating keratoplasty.

Biography

Hala El Mofty is working as a Professor of Ophthalmology, Faculty of Medicine, Cairo University. Born in Cairo, Egypt. Joined Cairo University Faculty of medicine

in 1977 and graduated with an excellent degree with honour and got residency in Cairo University hospitals (about 6000 beds). Ophthalmology department in Cairo

university hospitals is considered as a referral center from all over Egypt. Thus, practicing ophthalmology since 1985.

Head of ophthalmology department Misr University for science and Technology since 2015 with main interest in corneal infections and ophthalmology ultrasound.

Education and teaching undergraduate and postgraduates is my hobby.

Moreover interested in Research work and published a lot of national and international papers. Through my research achieved the patency of new topical drug for

treating fungal and acanthamoeba keratitis from Academy of Scientific Research in Cairo August 2005.

dr.halaelmofty@yahoo.com

Hala El Mofty, Optom open access 2017, 2:2 (Suppl)

DOI: 10.4172/2476-2075-C1-005