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conferenceseries
.com
Volume 4
Clinical Neuropsychology: Open Access
Neuropsychiatry 2018
August 27-28, 2018
August 27-28, 2018 Tokyo, Japan
8
th
Global Experts Meeting on
Advances in Neurology and Neuropsychiatry
Anxiety in patients with diabetic peripheral neuropathy
Katerina Stambolieva
1
and D Petrova
2
1
Institute of Neurobiology-BAS, Bulgaria
2
National Transport Hospital "Tzar Boris III", Bulgaria
Background:
Diabetic Peripheral Neuropathy (DPN) is one of the most common complications of diabetes mellitus which
usually affects peripheral nerves and leads to the tingling, pain and loss of sensation in the legs and postural instability that
worse the quality of life and often provokes anxiety and depression on some of patients with DPN.
Aim:
The aim of this study was to evaluate the prevalence rate of anxiety in the patients with DPN before and after combined
therapy with Alpha-Lipoic Acid (ALA) and benfotiamin, pyridoxine and cyancobalamine together.
Patients &Methods:
Sixty-four (64) patients with main duration of DPN 8.5±4.7 years and aged between 50 and 65 years took
part in this investigation. All patients were treated with combined therapy. The degree of anxiety in patients was evaluated by
Hospital Anxiety and Depression Scale (HADS) and the postural stability-by using static posturography. The investigations
were made on the first and 60
th
day after the therapy.
Results:
Before treatment all patients demonstrated high postural instability. Middle level of anxiety (HADS_A mean score
12.2±1.9) persisted in 47.8% of patients with DPN. The correlation between duration of diabetes and DPN and anxiety are
not observed. After treatment with combined therapy the symptoms of DPN such as tingling, and pain of legs decrease. An
improvement of the postural instability and decrease of the level of anxiety (HADS_A mean score 8.6±1.3) were observed.
Conclusion:
Treatment with combined therapy decrease the naturopathic symptomatic and level of anxiety caused to
improvement the quality of life of patient with DPN.
Biography
Katerina Stambolieva is an Associate Professor of Physiology at the Institute of Neurobiology at the Bulgarian Academy of Sciences. Her scientific interests are
in the field of neurophysiology, posture and equilibrium, prevention and treatment of diseases of the peripheral nervous system, motor and cognitive behavior and
vestibular rehabilitation.
katerina_stambolieva@yahoo.comKaterina Stambolieva et al, ClinNeuropsychol 2018, Volume 3
DOI: 10.4172/2472-095X-C1-003