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Volume 9
Journal of Analytical & Bioanalytical Techniques
Mass Spectra & Analytika 2018
September 19-20, 2018
September 19-20, 2018 Singapore
World Congress on
Mass Spectrometry and Analytical Techniques
J Anal Bioanal Tech 2018, Volume 9
DOI: 10.4172/2155-9872-C2-031
Analytical characteristics of nanoelectrospray operated under super-atmospheric pressure
Md Matiur Rahman
1
and Lee Chuin Chen
2
1
Beijing Institute of Technology, China
2
University of Yamanashi, Japan
H
igh-pressure nanoelectrospray ionization (nanoESI) source is a recently developed technique in which the electrospray
ionization is generated inside an enclosed chamber with gas pressure higher than the atmospheric pressure. In this paper,
the performance of nanoESI under different gas pressures, emitter position, ion inlet temperature, additive for desalination are
presented. Under a pressure of 2 bars, the nanoESI is almost eased from the electrical discharge problem and that offers a wider
tuning window for the emitter potential to produces a higher and more stable ion signal. With optimized ion inlet temperature,
the high-pressure operation facilitates the generation of ion species of higher charge-state from the highly aqueous solution
and produced less sodium adducts. A preparation method for the high-throughput analysis of raw biological samples using
disposable plastic nanoESI emitter could be described.
matiurrahmanbot@yahoo.com